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Imatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigationalBrian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy". … [A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr.
Products: IMATINIB EG, IMATENIL 200 MG KAPSÜL, 60 ADETFentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin.
Products: FENTANEST 500 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ (10 ADET), FENTANEST 100 MG/2 ML IV ENJEKSİYONLUK ÇÖZELTİ (10 ADET)Selexipag
go.drugbank.com/drugs/DB11362ApprovedInvestigationalSelexipag was approved by the United States FDA on December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and reduce risk of hospitalization. PAH is a relatively rare disease with usuall...
Products: UPTRAVI 1200 MCG FILM KAPLI TABLET, 60 ADET, SELPENZA 1200 MCG FİLM KAPLI TABLET, 60 ADETOxcarbazepine
go.drugbank.com/drugs/DB00776ApprovedInvestigational[L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood
Synonyms: 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamideProducts: TRILEPTAL 60 MG/ML ORAL SUSPENSION, Trileptal 60 mg/ml - Suspension zum EinnehmenDasatinib
go.drugbank.com/drugs/DB01254ApprovedInvestigationalBCR-ABL is associated with the uncontrolled activity of the ABL tyrosine kinase and is involved in the pathogenesis of CML and 15-30% of ALL cases.
Synonyms: N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideProducts: DASATINIB EG, Dasavec 20 mg Film Kaplı Tablet, 60 ADETAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approved(From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Products: ANDAZOL 200 MG/10 ML SÜSPANSİYON, 60 ML, ANDAZOL 200 MG/10 ML SÜSPANSİYON, 20 MLPiracetam
go.drugbank.com/drugs/DB09210ApprovedWithdrawnIt is not approved for any medical or dietary use by the FDA. … It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA).
Products: NOOTROPIL INFUSION INTRAVENOSA 12G/ 60 ML, BIOCETAM KAPSÜL, 60 ADETDabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigationalDabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran. Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom ...
Products: PRADAXA 110 MG SERT KAPSUL, 60 ADET, PRADAXA 150 MG SERT KAPSUL, 60 ADETAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigationalAlso known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate … More recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate
Products: STRATTERA 60 MG, audalis 60 mg FilmtablettenDenosumab
go.drugbank.com/drugs/DB06643ApprovedInvestigationalIt further received additional indication approval to increase bone mass in men at high risk for fracture receiving androgen deprivation therapy for non-metastatic prostate cancer and women at high risk … It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss.
Products: XGEVA® 120 MG/1.7 ML, XGEVA Solution for Injection 120 mg/vial