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Olezarsen
go.drugbank.com/drugs/DB18728ApprovedInvestigational[A264888,A264893] Olezarsen is conjugated to a ligand containing three N-acetyl-galactosamine (GalNAc) residues to enable its delivery to hepatocytes. … Olezarsen is an antisense oligonucleotide that targets the messenger RNA (mRNA) for apolipoprotein C-III (APOC3, apoC-III),[L52033] which is a key regulator of triglyceride levels in plasma, in the liver
Synonyms: DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-M5C-T-T-G-T-M5C-M5C-A-G-M5C-(2'-O-(2-METHOXYETHYL), -D-GALACTOPYRANOSYLOXY)HEXYLAMINO)-3-OXOPROPOXYMETHYL))METHYL)AMINO-5-OXOPENTANAMIDO)HEXYL))PHOSPHO)-2'-O-(2-METHOXYETHYL)-P-THIOADENYLYL-(3'-O->5'-O)-2'-O-(2-METHOXYETHYL)-P-THIOGUANYLYL-(3Copanlisib
go.drugbank.com/drugs/DB12483ApprovedInvestigationalCopanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. … PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies.
Synonyms: 2-AMINO-N-(7-METHOXY-8-(3-(MORPHOLIN-4-YL)PROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL(PYRIMIDINE-5-CARBOXAMIDE, 2-AMINO-N-(7-METHOXY-8-(3-MORPHOLIN-4-YLPROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL)PYRIMIDINE-5-CARBOXAMIDECategories: MATE 2 Inhibitors, Heterocyclic Compounds, 2-Ring2-ethylhexyl benzoate
go.drugbank.com/drugs/DB11291ApprovedWithdrawnSynonyms: 2-Ethyl-1-hexanol benzoate2'-fluoro-5-ethylarabinosyluracil
go.drugbank.com/drugs/DB13030Investigational2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-Fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil, 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil2'-Deoxycytidine 5'-triphosphate
go.drugbank.com/drugs/DB03258ExperimentalCategories: Heterocyclic Compounds, 1-RingSynonyms: 2'-Deoxycytidine 5'-triphosphate, 2'-Deoxycytidine-5'-Triphosphate5-(2-CHLOROBENZYL)-2-FUROIC ACID
go.drugbank.com/drugs/DB07308ExperimentalSynonyms: 5-(2-CHLOROBENZYL)-2-FUROIC ACID5-(2-METHOXYPHENYL)-2-FUROIC ACID
go.drugbank.com/drugs/DB07407ExperimentalSynonyms: 5-(2-METHOXYPHENYL)-2-FUROIC ACID5-(2-chlorophenyl)furan-2-carbohydrazide
go.drugbank.com/drugs/DB08757ExperimentalSynonyms: 5-(2-chlorophenyl)furan-2-carbohydrazideIndomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalsuperficial punctate keratitis and subjective symptoms of discomfort, including pain, burning or pricking, or a tingling sensation after instillation into the cul‐de‐sac. … NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole
Synonyms: 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acidInternational brands: Nu-Indo