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Dutasteride
go.drugbank.com/drugs/DB01126ApprovedInvestigationalDutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible...
Mixtures: ZIVATA-DUO, ASOFLON-DUOhumanized SMART Anti-IL-12 Antibody
go.drugbank.com/drugs/DB05848ExperimentalSMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La Roche Inc … IL-12 is a cytokine that may have considerable potential as a target in the therapy of autoimmune diseases.
Synonyms: humanized SMART Anti-IL-12 AntibodyNorclozapine
go.drugbank.com/drugs/DB05766InvestigationalACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA as a novel, stand-alone therapy for schizophrenia. It combines an atypical antipsychotic efficacy profile with the added potential b...
Piperonyl butoxide
go.drugbank.com/drugs/DB09350ApprovedVet approvedPiperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist. It has no pesticidal activity of its own...
Mixtures: Dg Health Lice Killing Maximum Strength, Lice-Nil Lice and Eggs KillerOat
go.drugbank.com/drugs/DB10546ApprovedOat allergenic extract is used in allergenic testing.
Mixtures: Aveeno Moisturizing Shower and Bath Oil, Aveeno Moisturizing Shower and Bath OilProducts: Aveeno Shower & Bath OilLemborexant
go.drugbank.com/drugs/DB11951ApprovedInvestigational[zopiclone], [zolpidem], benzodiazepines) focus on enhancing sleep drive via modulation of GABA and melatonin receptors, lemborexant and other orexin antagonists (e.g.
Recombinant stabilized RSV A prefusion F antigen
go.drugbank.com/drugs/DB18713ApprovedInvestigational[L49555] Abrysvo was approved for the same indications in the EU in August 2023[L49565] and Canada in December 2023.
Autologous peripheral blood-derived CD34+ cells
go.drugbank.com/drugs/DB16367ApprovedInvestigationalAutologous peripheral blood-derived CD34+ cells, or CLBS119 (a proprietary version being developed by Caladrius Biosciences, Inc.), are hematopoietic stem cells. It is also a cell therapy being investigated by Caladrius Biosciences in th...
Smallpox (Vaccinia) Vaccine, Live
go.drugbank.com/drugs/DB14711ApprovedInvestigationalThe New York City Board of Health strain of Vaccinia is a viral strain used as a component of some smallpox vaccinations. ACAM2000, a percutaneously administered smallpox vaccine that was approved by the FDA in 2007, contains live antige...
Rifapentine
go.drugbank.com/drugs/DB01201ApprovedInvestigationalRifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian ...