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Smallpox (Vaccinia) Vaccine, Live is a live Vaccinia virus strain used to induce active immunity to smallpox and mpox in high-risk patients. The New York City Board of Health strain of Vaccinia is a viral strain used as a component of some smallpox vaccinations.
- Mechanism
- Curator reviewed · 2 references
Smallpox vaccines, unlike most vaccinations, are administered via percutaneous scarification. A bifurcated needle containing live antigen is used to prick the skin several times within a small area, eliciting a local reaction that results in the formation of a pustule indicative of the successful development of protective immunity.
- Primary indication
- The live antigen of the New York City Board of Health strain of Vaccinia is indicated (within the ACAM2000 formulation) for active immunization against both smallpox and mpox disease in patients determined to be at...Curator reviewed · 2 structured indications
- First approval
- Canada, 2023 · United States, 2007
- Also known as
- Smallpox vaccine · Vaccinia virus live antigen, B · Vaccinia virus strain new york city board of health live (attenuated) antigen · Vaccinia virus strain new york city board of health live antigen · Vaccininum
- Brand names
- Acam2000
Resolves to
What you can answer from here — as of March 06, 2025
Which other approved drugs treat the same conditions as Smallpox (Vaccinia) Vaccine, Live, and which companies have late-stage candidates in those indications?