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ALMB-0166
go.drugbank.com/drugs/DB17937InvestigationalALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of acute spinal cord injury. It was granted FDA orphan designation in November 2018.[L47067]
RGX-181
go.drugbank.com/drugs/DB17942ExperimentalRGX-181 consists of an adeno-associated virus serotype 9 (AAV9) vector designed to deliver the soluble lysosomal enzyme tripeptidyl peptidase I (TPP1) gene. … Developed by REGENXBIO, it is being investigated for the treatment of late-infantile neuronal ceroid lipofuscinosis type 2 (CLN2) disease.[L47072]
AVXS-301
go.drugbank.com/drugs/DB17943ExperimentalAVXS-301 consists of an adeno-associated virus serotype 9 (AAV9) designed to express the superoxide dismutase 1 (SOD1) gene.
Bepranemab
go.drugbank.com/drugs/DB17945InvestigationalBepranemab is a recombinant humanized Igg4P monoclonal antibody directed against human Tau.
Synonyms: Immunoglobulin g4 (226-proline), anti-(human tau protein) (human-rattus norvegicus monoclonal ucb0107 .gamma.4-chain), disulfide with human-rattus norvegicus monoclonal ucb0107 .kappa.-chain, dimerRPI-MN
go.drugbank.com/drugs/DB17957ExperimentalRPI-MN is a detoxified or chemically modified alpha-cobratoxin with antiviral properties.
SRP-9005
go.drugbank.com/drugs/DB17958InvestigationalSRP-9005 is a rAAVrh74 vector containing a codon-optimized human SGCG transgene.
PIKA rabies vaccine
go.drugbank.com/drugs/DB17963InvestigationalPIKA rabies vaccine is a novel vaccine developed by YS Biopharma.
HOV-12020
go.drugbank.com/drugs/DB17976InvestigationalHOV-12020 is a palm tocotrienols complex being investigated for the treatment of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).[L47271]
Dazucorilant
go.drugbank.com/drugs/DB18025InvestigationalSynonyms: Methanone, ((4ar)-1-(4-fluorophenyl)-1,4,5,6,7,8-hexahydro-6-((4-(trifluoromethyl)phenyl)sulfonyl)-4ah-pyrazolo(3,4-g)isoquinolin-4a-yl)-2-pyridinyl-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingEmavusertib
go.drugbank.com/drugs/DB18060InvestigationalSynonyms: 4-oxazolecarboxamide, n-(5-((3r)-3-hydroxy-1-pyrrolidinyl)-2-(4-morpholinyl)oxazolo(4,5-b)pyridin-6-yl)-2-(2-methyl-4-pyridinyl)-Categories: Heterocyclic Compounds, 1-Ring