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Benzylpenicillin
go.drugbank.com/drugs/DB01053ApprovedInvestigationalVet approvedThe natural penicillins may also be used as first or second line agents against susceptible gram positive aerobic bacilli such as *Bacillus anthracis*, *Corynebacterium diphtheriae*, and *Erysipelothrix … Penicillin G may also be used in some cases as prophylaxis against susceptible organisms.
Lisinopril
go.drugbank.com/drugs/DB00722ApprovedInvestigational[A184853] It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system. … [A184844] Lisinopril was granted FDA approval on 29 December 1987.[L8384]
Lanolin alcohols
go.drugbank.com/drugs/DB14181ApprovedIt is administered as an ointment base with topical insulin and has shown to be antagonistic to wound healing. It is commonly used in allergenic testing.
Tadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigationalIn contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment … [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH.
Aliskiren
go.drugbank.com/drugs/DB09026ApprovedInvestigational[A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. … [L14018] Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in conjunction with other antihypertensive agents.[A203624]
Ticlopidine
go.drugbank.com/drugs/DB00208ApprovedTiclopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin or in whom aspirin has not worked to prevent a thrombotic stroke.
Technetium Tc-99m disofenin
go.drugbank.com/drugs/DB09164ApprovedWithdrawnfor liver uptake) as are other tracers from the iminodiacetic acid. … It is available as an intravenous injection in a preparation kit under the name Hepatolite.
Ranolazine
go.drugbank.com/drugs/DB00243ApprovedInvestigationalIt was originally approved by the FDA in 2006.[L5440]
Nabiximols
go.drugbank.com/drugs/DB14011Investigationalisomer as [DB00470], or in a 1:1 formulation with CBD from purified plant extract as [DB14011]. … For trademark purposes, purified CBD is branded as Nabidiolex®, while THC is purified as the product Tetrabinex®.
Ergoloid mesylate
go.drugbank.com/drugs/DB01049Approved[L2639]Later in 1991, the mixture of ergoloid mesylates was retaken by Sun Pharmaceutical Industries and approved by the FDA. … [A32914] The mixture of ergoloid mesylate was first developed by Novartis and FDA approved on November 5, 1953, but this specific formulation is now discontinued.