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Bucindolol
go.drugbank.com/drugs/DB12752InvestigationalBucindolol has been investigated in Heart Failure.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesResmetirom
go.drugbank.com/drugs/DB12914ApprovedInvestigationalResmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alc...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsGallopamil
go.drugbank.com/drugs/DB12923InvestigationalGallopamil has been used in trials studying the treatment of Asthma.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCafedrine
go.drugbank.com/drugs/DB12926InvestigationalCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesTheodrenaline
go.drugbank.com/drugs/DB12927InvestigationalTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesTirilazad
go.drugbank.com/drugs/DB13050InvestigationalTirilazad has been used in trials studying the treatment of Spinal Cord Injury.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNorflurane
go.drugbank.com/drugs/DB13116ApprovedInvestigationalWithdrawnNorflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesArtemisinin
go.drugbank.com/drugs/DB13132InvestigationalArtemisinin has been used in trials studying the treatment of Schizophrenia, Malaria, Falciparum, and Plasmodium Falciparum.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersCoagulation factor X human
go.drugbank.com/drugs/DB13148ApprovedInvestigationalCoagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for th...
Mixtures: Beriplex P/n 500, Beriplex P/n 1000Protein S human
go.drugbank.com/drugs/DB13149ApprovedInvestigationalProtein S human is a vitamin K-dependent plasma glycoprotein which has antcoagulant properties . It serves as a negative feedback mechanism in the coagulation cascade.
Mixtures: Beriplex P/n 500, Beriplex P/n 1000