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Oxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigationalOxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. … Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect.
Synonyms: (SP-4-2-(1R-TRANS))-(1,2-CYCLOHEXANEDIAMINE-N,N')(ETHANEDIOATO(2-)-O,O')PLATINUM, L-OHPCategories: OCT2 Substrates with a Narrow Therapeutic IndexCitrulline
go.drugbank.com/drugs/DB00155InvestigationalNutraceuticalIt is also produced from arginine as a by-product of the reaction catalyzed by NOS family. Its name is derived from citrullus, the Latin word for watermelon, from which it was first isolated.
Synonyms: 2-Amino-5-ureidovaleric acid, (S)-2-Amino-5-ureidopentanoic acidProducts: STIMOL ORAL SOLUTION 1g/10mlAlprostadil
go.drugbank.com/drugs/DB00770ApprovedInvestigationalAlprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. … [A257068,A257088] Alprostadil is also used in neonatal patients with congenital heart defects that depend on a patent ductus for survival until corrective or palliative surgery can be performed.
Categories: Prostaglandins ESynonyms: (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate, (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acidLinafexor
go.drugbank.com/drugs/DB18031InvestigationalSynonyms: 1,2,4-OXADIAZOL-5(2H)-ONE, 3-(4-(3-((5-CYCLOPROPYL-3-(2,6-DICHLOROPHENYL)-4-ISOXAZOLYL)METHOXY)-8-AZABICYCLO(3.2.1)OCT-8-YL)-2-FLUOROPHENYL)-, 3-(4-((3-endo)-3-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4- yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-2-fluorophenyl)-1,2,4-oxadiazol-5(4H)-oneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesFenofibrate
go.drugbank.com/drugs/DB01039ApprovedInvestigational[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585] … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.
Synonyms: 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester, Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionateMixtures: STAFEN 135/10 MG CAPSULAS, STAFEN 135/10 MG CAPSULASMedroxyprogesterone acetate
go.drugbank.com/drugs/DB00603ApprovedInvestigationalMedroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.
Synonyms: (6α)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione, 6-alpha-Methyl-17-alpha-acetoxyprogesteroneMixtures: DIVICONT TABLETAS 1 MG/5 MG, DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADETGemcitabine elaidate
go.drugbank.com/drugs/DB12564InvestigationalGemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.
Synonyms: 2'-Deoxy-2',2'-difluorocytidine 5'-(9E)-octadec-9-enoate, 5'-O-(trans-9"-octadecenoyl)-1-beta-D-2'deoxy-2',2'-difluorocytidineCategories: Heterocyclic Compounds, 1-RingPhenazepam
go.drugbank.com/drugs/DB19164InvestigationalPhenazepam is under investigation in clinical trial NCT03017430 (Pregabalin for Opiate Withdrawal Syndrome).
Synonyms: 2h-1,4-benzodiazepin-2-one, 1,3-dihydro-7-bromo-5-(2-chlorophenyl)-, 2h-1,4-benzodiazepin-2-one, 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-Categories: Heterocyclic Compounds, 2-RingTuvusertib
go.drugbank.com/drugs/DB18790InvestigationalSynonyms: 2-amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamideImolamine
go.drugbank.com/drugs/DB09284InvestigationalImolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl-4,5-dihydro-1,2,3-oxadiazol,-4-yl)ethyl]amine.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-Phenyl-4-diethylaminoethyl-5-imino-1,2,4-oxadiazol