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Vamorolone
go.drugbank.com/drugs/DB15114ApprovedInvestigationaland the most common form of muscular dystrophy in the United States. … [L48676] Vamorolone was approved by the FDA in October 2023 for the management of DMD in patients ≥2 years of age.
Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, PlainHuman botulinum neurotoxin A/B immune globulin
go.drugbank.com/drugs/DB14115Approved[L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in 2003[L39814] and has since been used to treat more than 2100 cases of infant botulism. … [L39834] It is produced and distributed by the Calfornia Department of Public Health's Infant Botulism Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma
Ardeparin
go.drugbank.com/drugs/DB00407ApprovedWithdrawnNormiflo was withdrawn from the US market in March 2000. … Ardeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis.
Acetrizoic acid
go.drugbank.com/drugs/DB09347ApprovedWithdrawn[A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th, 1978.
Categories: Compounds used in a research, industrial, or household settingBromocriptine
go.drugbank.com/drugs/DB01200ApprovedInvestigationalWithdrawnIn 1995, the FDA withdrew the approval of bromocriptine mesylate for the prevention of physiological lactation after finding that bromocriptine was not shown to be safe for use. … [L43942,L43947] It continues to be used for the indications mentioned above.
Categories: Heterocyclic Compounds with 4 or More RingsNefazodone
go.drugbank.com/drugs/DB01149ApprovedWithdrawnOn May 20, 2004, Bristol-Myers Squibb discontinued the sale of Serzone in the United States. … Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with the incidence of severe liver damage was shown to be approximately 1 in 250,000 to
Categories: Antidepressive Agents Indicated for DepressionParoxetine
go.drugbank.com/drugs/DB00715ApprovedInvestigational[T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham.
Categories: Antidepressive Agents Indicated for DepressionCyclothiazide
go.drugbank.com/drugs/DB00606ApprovedIt is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. … The antihypertensive mechanism of cyclothiazide is less well understood although it may be mediated through its action on carbonic anhydrases in the smooth muscle or through its action on the large-conductance
Neurotrophic factor BDNF precursor form
go.drugbank.com/bio_entities/BE0003394TargetHumansImportant signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed:11152678). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous sy...
Polypeptides: Neurotrophic factor BDNF precursor formBempedoic acid
go.drugbank.com/drugs/DB11936ApprovedInvestigationalCaused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. … High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events.
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia