Search
Selinexor
go.drugbank.com/drugs/DB11942ApprovedInvestigationalSelinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound. … Selinexor, in combination with [bortezomib] and [dexamethasone], is currently approved for the treatment of multiple myeloma, a type of cancer formed from antibody-producing plasma cells.
Indigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigationalIndigotindisulfonic acid is a blue-colored dye with a variety of uses. … [A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2.
Categories: Compounds used in a research, industrial, or household setting, Tests for Renal Function and Ureteral InjuriesInfluenza A virus A/Brisbane/02/2018 IVR-190 (H1N1) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15515ApprovedInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Mixtures: Influvac Tetra, suspension for injection in pre-filled syringe, INFLUVAC TETRA, SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 MLSynonyms: Influenza A virus A/Brisbane/02/2018 IVR-190 (H1N1) antigen (formaldehyde inactivated)Temozolomide
go.drugbank.com/drugs/DB00853ApprovedInvestigationalRefractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. … [A229853, A229888, A229923, L32033] Following initial hydrolysis, further reactions liberate a highly reactive methyl diazonium cation capable of methylating various residues on adenosine and guanine bases
Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: TEMODAL 140MG HKP IN BTL, TEMODAL 180MG HKP IN BTLRurioctocog alfa pegol
go.drugbank.com/drugs/DB16007ApprovedInvestigationalFactor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous … or secondary events like trauma or surgery.
Products: ADYNOVATE 1500IU Powder and Solvent for Solution for Injection, ADYNOVATE 2000IU Powder and Solvent for Solution for InjectionCollagenase clostridium histolyticum
go.drugbank.com/drugs/DB00048ApprovedInvestigational[L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA for the treatment of cellulite in adult women. … It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease.
Categories: Preparations for Treatment of Wounds and UlcersSynonyms: Clostridiopeptidase AHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus … [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.
Products: AA PHARMA HYDROXYZINE CAPSULE 10 mg, AA PHARMA HYDROXYZINE CAPSULE 25 mgThiosulfuric acid
go.drugbank.com/drugs/DB09499ApprovedInvestigational[A252827] Sodium thiosulfate is approved for the treatment of acute cyanide poisoning[L310,L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). … [A252827] Sodium thiosulfate is rapidly degraded in the stomach; therefore, it is normally administered through other routes, such as intravenous or topical.
Categories: Compounds used in a research, industrial, or household settingTegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawnin female patients less than 65 years of age and whom are considered to be at a lower risk of a cardiovascular event than the broader population. … [L5918,F4229] Since then, closer evaluations of the original data suggesting such cardiovascular risk have resulted in the limited reintroduction or 're-approval' of tegaserod for treatment of IBS-C specifically
Categories: Drugs for ConstipationRamelteon
go.drugbank.com/drugs/DB00980ApprovedInvestigationalRamelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). … It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.