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Darvadstrocel
go.drugbank.com/drugs/DB16581ApprovedInvestigationalWithdrawnIt is indicated for the treatment of complex perianal fistulas in adult patients with non-active or mildly active luminal Crohn’s disease when fistulas have shown an inadequate response to at least one … Perianal fistula is a common manifestation of Crohn’s disease and is often difficult to manage, as it may be associated with complex presentations and symptoms.
Urea C-13
go.drugbank.com/drugs/DB09510ApprovedInvestigationalExhaled breath samples can then be collected and measured for the presence of radioactivity. … Both forms can be used within the Urea Breath Test, however some may prefer 13C as it is non-radioactive compared to 14C, which may be preferable in pregnant women and children.
Products: Helicobacter Test Infai for Children Of The Age 3-11Pirfenidone
go.drugbank.com/drugs/DB04951ApprovedInvestigational[A251370] It is an antifibrotic agent with anti-inflammatory and antioxidant properties [A251370] that is used to treat idiopathic pulmonary fibrosis (IPF),[L26801] which is a chronic, progressive form … [A251370] While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate tumor necrosis factor (TNF) pathways and modulate cellular oxidation.
Products: Pirfenidone Aet, PİRFECT 200 MG FİLM TABLET, 252 ADETDacomitinib
go.drugbank.com/drugs/DB11963ApprovedInvestigationalDacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible … binding at the ATP domain of the epidermal growth factor receptor family kinase domains.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: VİZİMPRO 15 MG FİLM KAPLI TABLET, 30 ADET, VİZİMPRO 30 MG FİLM KAPLI TABLET, 30 ADETTenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigational[T239] Tenofovir alafenamide is an alanine ester form characterized for presenting low systemic levels but high intracellular concentration. … [A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir disoproxil.
Mixtures: DESCOVY 200 MG/ 10 MG FILM KAPLI TABLET, 30 ADET, DESCOVY 200 MG/ 10 MG FILM KAPLI TABLET, 90 ADETCategories: Antivirals used in combination for the treatment of HIV infectionsClodronic acid
go.drugbank.com/drugs/DB00720ApprovedInvestigationalVet approved[A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. … Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid].
Categories: Drugs for Treatment of Bone DiseasesProducts: BONEFOS 800 MG TABLET, 60 ADETCilgavimab
go.drugbank.com/drugs/DB16393ApprovedInvestigationalhistory of SARS-CoV-2 infection and modified through targeted amino acid substitutions to exhibit an extended (~85-day) half-life. … Cilgavimab, in combination with [tixagevimab], was issued an FDA emergency use authorization (EUA) on December 9, 2021, for the pre-exposure prophylaxis of COVID-19 in individuals at increased risk for
Tixagevimab
go.drugbank.com/drugs/DB16394ApprovedInvestigationalnatural history of SARS-CoV-2 infection and modified through targeted amino acid substitutions to exhibit an extended (~85-day) half-life. … Tixagevimab, in combination with [cilgavimab], was issued an FDA emergency use authorization (EUA) on December 9, 2021, for the pre-exposure prophylaxis of COVID-19 in individuals at increased risk for
2-deoxyglucose
go.drugbank.com/drugs/DB08831InvestigationalBy using positron emission tomography (PET), radiolabelled 2-deoxyglucose can determine glucose metabolism, which is altered in diseases such as cardiovascular disease, tumors, and Alzheimer's disease. … As an experimental drug, 2-deoxyglucose was demonstrated to work as an anticonvulsant in temporal lobe epilepsy.
Pretomanid
go.drugbank.com/drugs/DB05154ApprovedInvestigational[A182915] Pretomanid is an antimycobacterial agent that is administered with [Bedaquiline] and [Linezolid] to treat resistant forms of pulmonary TB. … Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern.
Categories: Drugs for Treatment of Tuberculosis