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Displaying results 1341 - 1350 of 10000 in total
  1. Drug

    Leuvectin

    go.drugbank.com/drugs/DB17303
    Investigational

    Leuvectin (formerly known as VCL-1102) is a component of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE

    Categories: Gene Transfer TechniquesSynonyms: DNA-lipid complex (DMRIE/DOPE)/plasmid vector (VCL-1102, Vical) expressing human interleukin-2
  2. Drug

    Triflusal

    go.drugbank.com/drugs/DB08814
    ApprovedWithdrawn

    Triflusal is a 2-acetoxy-4-trifluoromethylbenzoic acid and it is an aspirin chemically-related molecule but not a derivative. … [A31675] It is very important as a secondary prevention of ischemic stroke by offering a lower risk of bleeding.[A31676] It was developed by J.

  3. Drug

    Diethylamino hydroxybenzoyl hexyl benzoate

    go.drugbank.com/drugs/DB11269
    Approved

    Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. … It has a chemical structure similar to the classical benxophoenone drug class, and displays good photostability [A33171].

    Mixtures: Fascy Lab Green Plus Sun, PURITO Centella Green Level Safe SunSynonyms: Hexyl 2-(4-(diethylamino)-2-hydroxybenzoyl)benzoate
  4. Drug

    Prasterone

    go.drugbank.com/drugs/DB01708
    ApprovedInvestigationalNutraceutical

    In the United States, DHEA or DHEAS have been advertised with claims that they may be beneficial for a wide variety of ailments. … In Canada, a prescription is required to buy DHEA.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: 3-beta-hydroxy-5-androsten-17-one, 3β-hydroxyandrost-5-en-17-one
  5. Drug

    Entrectinib

    go.drugbank.com/drugs/DB11986
    ApprovedInvestigational

    [L8081] It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. … Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide
  6. Drug

    Erdafitinib

    go.drugbank.com/drugs/DB12147
    ApprovedInvestigational

    tool kit to treat such a prevalent medical condition. … In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for

    Categories: Fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitors, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: BALVERSA 3 MG FÄ°LM KAPLI TABLET, 56 ADET, BALVERSA 3 MG FÄ°LM KAPLI TABLET, 84 ADET
  7. Drug

    Luspatercept

    go.drugbank.com/drugs/DB12281
    ApprovedInvestigational

    Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1. … [A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients with beta thalassemia who require regular blood

    Products: REBLOZYL®
  8. Drug

    Etoperidone

    go.drugbank.com/drugs/DB09194
    ApprovedWithdrawn

    It is a phenylpiperazine-substituted triazole derivative with a composition that classifies it as an analog of tradozone and presents a similar pharmacological profile.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor Antagonists
  9. Drug

    L-Acetylleucine

    go.drugbank.com/drugs/DB16956
    ApprovedInvestigational

    Levacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo. … [A264439] Observational studies in patients with Niemann-Pick disease type C (NPC) suggested a beneficial symptomatic as well as neuroprotective disease-modifying effect of the DL-form of N-acetylleucine

    Categories: P-glycoprotein inhibitorsSynonyms: (s)-2-acetamido-4-methylpentanoic acid, L-leucine, n-acetyl-
  10. Drug

    Potassium

    go.drugbank.com/drugs/DB14500
    ApprovedInvestigational

    [A32222,A38081,L2652] Various pharmacological preparations have been formulated to replenish potassium. … It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans.

    Mixtures: GNC Mega Teen, Jba Ativ Electrolyte Ors Lavender LemonadeSynonyms: K