Triflusal is a medication related to acetylsalicylic acid with antithrombotic effects used in the treatment of thromboembolic diseases. Triflusal is a 2-acetoxy-4-trifluoromethylbenzoic acid and it is an aspirin chemically-related molecule but not a derivative.
- Mechanism
- Curator reviewed · 1 reference
Triflusal is chemically related to acetylsalicylic acid (ASA) and irreversibly inhibits cycloxygenase-1 (COX-1) in platelets. Acetylation of the active group of COX-1 prevents the formation of thromboxane-B2 in platelets. However, it is unique because it spares the arachidonic acid metabolic pathway in endothelial cells. In addition, it favors the production of nitric oxide, a vasodilator.
- Primary indication
- Triflusal is indicated as prophylaxis of thromboembolic disorders.Curator reviewed · 3 structured indications
- Formula / weight
- C10H7F3O4 · 248.157 g/mol (avg)
- Code names
- UR-1501
Resolves to
RMWVZGDJPAKBDE-UHFFFAOYSA-NSMILESCC(=O)OC1=C(C=CC(=C1)C(F)(F)F)C(O)=OWhat you can answer from here — as of March 06, 2025
Which drugs share a target with Triflusal, and which of those have an active Phase 3 trial?
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