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Tauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawn[A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as a bile acid derivative. … Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration.
Tirzepatide
go.drugbank.com/drugs/DB15171ApprovedInvestigational[L48766] On September 15, 2022, tirzepatide was also approved by the European Commission.[L44386]. On November 02, 2023, tirzepatide was also approved by the Health Canada [L52800] … Dual GIP/GLP-1 agonists gained increasing attention as new therapeutic agents for glycemic and weight control as they demonstrated better glucose control and weight loss compared to selective GLP-1 receptor
Categories: Drugs Used in DiabetesProducts: Mounjaro 2.5 mg solution for injection in pre-filled pen, Mounjaro 5 mg solution for injection in pre-filled penAlogliptin
go.drugbank.com/drugs/DB06203ApprovedInvestigationalIt undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Mixtures: OSENI FILM COATED TABLET 25MG/ 15MG, OSENI FILM COATED TABLET 12.5MG/ 15MGCategories: Drugs Used in DiabetesBulevirtide
go.drugbank.com/drugs/DB15248ApprovedInvestigationalIt was first approved for use in the EU on May 28, 2020; bulevirtide has been granted PRIME scheme eligibility and Orphan Drug Designation by the European Medicines Agency. … [Peginterferon Alfa-2a]) in Patients With CHD.
Brexanolone
go.drugbank.com/drugs/DB11859ApprovedInvestigationalbrexanolone may also be undergoing clinical trials to investigate its abilities to treat super-refractory status epilepticus, it appears that some such studies have failed to meet primary endpoints that compare … In particular, the use of brexanolone in treating PPD is surrounded with promise because it acts in part as a synthetic supplement for possible deficiencies in endogenous brexanolone (allopregnanolone)
Diroximel fumarate
go.drugbank.com/drugs/DB14783ApprovedInvestigational[A176474] It is the main cause of neurological disability not caused by trauma in the young adult population of both North America and Europe. … Diroximel fumarate was formulated by Alkermes in collaboration with Biogen, and was approved by the FDA in October 2019[L9626] and by the EMA in November 2021.[L39225]
Bendroflumethiazide
go.drugbank.com/drugs/DB00436ApprovedInvestigationalIt has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Mixtures: Corzide Tab W Nadolol 80mg, Corzide Tab W Nadolol 40mgTezepelumab
go.drugbank.com/drugs/DB15090ApprovedInvestigational[L39504] Tezepelumab was also approved by the European Commission on September 19, 2022.[L44712] … It was granted FDA approval on December 17, 2021, and is currently marketed under the trademark TEZSPIRE by Amgen/AstraZeneca.
Racementhol
go.drugbank.com/drugs/DB14123ApprovedInvestigationalMixtures: Tommie Copper Sport, Tommie Copper Pain Relief RollerProducts: Tommie Copper Pain Relief, Nosk EX SleepNicoboxil
go.drugbank.com/drugs/DB12911ApprovedWithdrawnSuch combination topical analgesics are only available for purchase and use (for humans) in some parts of Europe and Asia, like Germany and Australia [F11, F16]. … and capability to be used as an alternative musculoskeletal pain therapy option with less systemic side effects when compared to the oral non-steroidal anti-inflammatory drugs and opioids that may be