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Iobenguane
go.drugbank.com/drugs/DB06704ApprovedInvestigationalThe radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline.
Categories: Compounds used in a research, industrial, or household settingBeremagene geperpavec
go.drugbank.com/drugs/DB17831ApprovedInvestigationalDeveloped by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). … [L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component of the anchoring fibrils for dermal–epidermal cohesion.
Categories: Preparations for Treatment of Wounds and UlcersCarbinoxamine
go.drugbank.com/drugs/DB00748ApprovedCarbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many
Categories: Antihistamines for Systemic UseNetarsudil
go.drugbank.com/drugs/DB13931ApprovedInvestigationalwith norepinephrine transport inhibitory activity that reduces production of aqueous As of December 18, 2017 the FDA approved Aerie Pharmaceutical's Rhopressa (netarsudil ophthalmic solution) 0.02% for … the indication of reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Adefovir dipivoxil
go.drugbank.com/drugs/DB00718ApprovedAdefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseVosoritide
go.drugbank.com/drugs/DB11928ApprovedInvestigationalapproved for the treatment of achondroplasia in both regions. … [A242273,A242277] Treatment for achondroplasia includes both surgical and pharmacological interventions, the latter of which includes C-type natriuretic peptide (CNP) analogs.
Categories: Drugs for Treatment of Bone DiseasesRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. … In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547].
Streptococcus pneumoniae type 5 capsular polysaccharide antigen
go.drugbank.com/drugs/DB10323ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Mixtures: PREVENAR 13 SUSPENSION FOR INJECTION, Prevenar 13 Suspension For InjectionStreptococcus pneumoniae type 23f capsular polysaccharide antigen
go.drugbank.com/drugs/DB10340ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Mixtures: PREVENAR 13 SUSPENSION FOR INJECTION, Prevenar 13 Suspension For InjectionLincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approvedLincomycin is a lincosamide antibiotic first isolated from the soil bacterium Streptomyces lincolnensis in Lincoln, Nebraska. Clinical use of lincomycin has largely been superseded by its semisynthetic derivative clindamycin due to its h...
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use