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Displaying results 1381 - 1390 of 10000 in total
  1. Drug

    Cetuximab

    go.drugbank.com/drugs/DB00002
    ApprovedInvestigational

    [A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for the treatment of head and neck cancer and metastatic, KRAS wild-type colorectal cancer, and metastatic … [A227963,L39045] It has also been investigated in advanced colorectal cancer, EGFR-expressing non-small cell lung cancer (NSCLC), and unresectable squamous cell skin cancer.

    Products: ERBITUX 100 MG/20 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET, ERBITUX 500 MG/100 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET
  2. Target

    NF-kappa-B inhibitor alpha

    go.drugbank.com/bio_entities/BE0003469
    TargetHumans

    Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals (PubMed:1493333, PubMed:36651806, PubMed:7479976). On cellular stimu...

    Synonyms: I-kappa-B-alpha
  3. Pathway

    Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-12:0/i-13:0)

    smpdb.ca/view/SMP0051177
    Disease

    BTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  4. Pathway

    Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-12:0/i-14:0)

    smpdb.ca/view/SMP0051178
    Disease

    BTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  5. Pathway

    Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-12:0/i-18:0)

    smpdb.ca/view/SMP0051182
    Disease

    BTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  6. Pathway

    Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-13:0/i-12:0)

    smpdb.ca/view/SMP0051194
    Disease

    BTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  7. Pathway

    Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-13:0/i-20:0)

    smpdb.ca/view/SMP0051202
    Disease

    BTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  8. Pathway

    Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-13:0/i-22:0)

    smpdb.ca/view/SMP0051204
    Disease

    BTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  9. Pathway

    Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-13:0/i-24:0)

    smpdb.ca/view/SMP0051205
    Disease

    BTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  10. Pathway

    Cardiolipin Biosynthesis CL(i-12:0/i-12:0/i-14:0/i-12:0)

    smpdb.ca/view/SMP0051212
    Disease

    BTHS patients seem to lack acyl specificity and consequently, many potential cardiolipin species can exist (PMID: 16226238). … (Wikipedia) Cardiolipin biosynthesis occurs mainly in the mitochondria, but there also exists an alternative synthesis route for CDP-diacylglycerol that takes place in the endoplasmic reticulum.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate