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Displaying results 131 - 140 of 14148 in total
  1. Drug

    Etanercept

    go.drugbank.com/drugs/DB00005
    ApprovedInvestigational

    Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids.

    Synonyms: Recombinant human TNFCategories: Amino Acids, Peptides, and Proteins, Tumor Necrosis Factor Blockers
  2. Drug

    Recombinant Cholera Toxin B Subunit

    go.drugbank.com/drugs/DB11643
    ApprovedInvestigational

    Recombinant Cholera Toxin B Subunit is an ingredient in the EMA-authorised product Dukoral.

    Mixtures: DUKORAL VACCINE AGAINST CHOLERA AND ETEC-DIARRHOEACategories: Enzymes and Coenzymes, Biological Factors
  3. Drug

    Zenocutuzumab

    go.drugbank.com/drugs/DB15559
    ApprovedInvestigational

    Zenocutuzumab is a low-fucose humanized full-length immunoglobulin G1 (IgG1) bispecific HER2- and HER3-directed bispecific antibody. … [L51963] It works to attenuate aberrant cancer cell growth caused by genomic rearrangements involving the neuregulin 1 gene (NRG1), which is an oncogenic driver.

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized clone mcla-128 .gamma.1-chain), disulfide with humanized clone mcla-128 light chain, dimer, Mcla-128 (igg1 bispecific antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and her3 receptors.)
  4. Drug

    Human vaccinia virus immune globulin

    go.drugbank.com/drugs/DB14112
    ApprovedInvestigational

    Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human product that is only available in very limited quantities - all factors that may intervene with … its availability and effectiveness [A33798, A33814].

    Categories: Human Immunoglobulin G, Amino Acids, Peptides, and ProteinsSynonyms: Human vaccinia immune globulin, Human vaccinia virus immune globulin
  5. Drug

    Anti-inhibitor coagulant complex

    go.drugbank.com/drugs/DB13151
    ApprovedInvestigational

    It is used to control bleeding in hemophilia A and B patients with inhibitors. … Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex.

    Categories: Blood Coagulation Factors, Blood and Blood Forming OrgansSynonyms: Factor VIII bypassing fraction, Factor Eight Inhibitor Bypassing Activity
  6. Drug

    Laronidase

    go.drugbank.com/drugs/DB00090
    ApprovedInvestigational

    Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. … The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human a-L-iduronidase.

    Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: Human Recombinant alpha-L-iduronidase
  7. Drug

    Recombinant methionyl brain-derived neurotrophic factor

    go.drugbank.com/drugs/DB16970
    Investigational

    Synonyms: Recombinant methionyl human brain-derived neurotrophic factor, Recombinant methionyl human bdnf
  8. Drug

    Apitegromab

    go.drugbank.com/drugs/DB16096
    ApprovedInvestigational

    Apitegromab-mstn is a fully human IgG4 lambda monoclonal antibody produced by recombinant DNA technology in Chinese Hamster Ovary cells. … [L64184] Apitegromab-mstn was approved by the FDA in September 2026 under the brand name ISEMBYLD for the treatment of spinal muscular atrophy in adults and pediatric patients 2 years of age and older

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk-015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda.-chain, dimer
  9. Drug

    Trafermin

    go.drugbank.com/drugs/DB06244
    Investigational

    Synonyms: Recombinant human basic fibroblast growth factorCategories: Biological Factors, Fibroblast Growth Factors
  10. Drug

    Pegylated Recombinant Human Arginase I

    go.drugbank.com/drugs/DB16282
    Investigational

    Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)).

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: Pegylated Recombinant Human Arginase I, Pegylated recombinant human arginase i bct-100