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Displaying results 131 - 140 of 10000 in total
  1. Drug

    Brivaracetam

    go.drugbank.com/drugs/DB05541
    ApprovedInvestigational

    Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam [A19184]. It is available under the brand name Briviact made by UCB.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: BRIVIACT 10 MG/ML ENJEKSIYONLUK ÇÖZELTI, 10 ADET FLAKON, BRIVIACT®10 MG
  2. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    [L3754] It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. … [A181036,A181039] Metronidazole has been used as an antibiotic for several decades[L7429], with added antiparasitic properties that set it apart from many other antibacterial drugs, allowing it to treat

    Synonyms: 2-methyl-5-nitroimidazole-1-ethanol, 1-(β-oxyethyl)-2-methyl-5-nitroimidazoleMixtures: NEO-PENOTRAN 500 MG/ 100 MG OVUL, 14 ADET, NIDAZOL-M 500 MG/100 MG VAJİNAL TABLET, 14 ADET
  3. Drug

    Ketoprofen

    go.drugbank.com/drugs/DB01009
    ApprovedInvestigationalVet approved

    Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

    Synonyms: m-Benzoylhydratropic acidCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitors
  4. Drug

    Diazepam

    go.drugbank.com/drugs/DB00829
    ApprovedIllicitInvestigationalVet approved

    It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal … (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the

    Synonyms: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-oneMixtures: Gabavale-5
  5. Drug

    Tranexamic acid

    go.drugbank.com/drugs/DB00302
    ApprovedInvestigational

    It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent. … [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986.[L31858]

    Products: TRANSAMINE 500 MG FILM TABLET, 50 ADET, TRANSAMINE 50 MG/ML IV ENJ COZELTI, 5 ML
  6. Drug

    Ephedrine

    go.drugbank.com/drugs/DB01364
    ApprovedInvestigational

    Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine]. … [A193698] Ephedrine acts as both a direct and indirect sympathomimetic.

    Mixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, ARTU 100 ML SURUPProducts: Ephedrin Meduna 10 mg/ml Injektionslösung, Ephedrin Kabi 10 mg/ml Injektionslösung
  7. Drug

    Ketamine

    go.drugbank.com/drugs/DB01221
    ApprovedInvestigationalVet approved

    It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients undergoing minor surgeries but mainly for veterinary purposes.[L1332] … [A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: KETAX 500 MG/10 ML ENJEKSİYONLUK/ İNFÜZYONLUK ÇÖZELTİ, 1 ADET, Ketamin G.L. 10 mg/ml - Injektions-/Infusionslösung in Ampullen
  8. Drug

    Levosalbutamol

    go.drugbank.com/drugs/DB13139
    Approved

    [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. … The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol

    Mixtures: İPRALEV 20 MCG/50 MCG AEROSOL İNHALASYONU,SÜSPANSİYON, 200 DOZCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  9. Drug

    Maridebart Cafraglutide

    go.drugbank.com/drugs/DB19339
    Investigational

    Maridebart Cafraglutide is under investigation in clinical trial NCT05669599 (Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity

    Synonyms: gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-33*01 (92.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, Immunoglobulin G1, anti-(glucose-dependent insulinotropic polypeptide receptor) [275-cysteine,295-cysteine,300-glycine,305-cysteine] (human γ1-chain), disulfide with human κ-chain, dimer, 275,275′-bis(
  10. Drug

    Dyphylline

    go.drugbank.com/drugs/DB00651
    ApprovedWithdrawn

    Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.

    Mixtures: ESPEKTAN ŞURUP, 100 ML, ESPEKTAN A ŞURUP, 100 MLProducts: DIFILIN 400 MG SUPOZITUAR, 10 SUPOZITUAR, DIFILIN 400 MG SUPOZITUAR, 50 SUPOZITUAR