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Displaying results 1391 - 1400 of 2250 in total
  1. Drug

    Remdesivir

    go.drugbank.com/drugs/DB14761
    ApprovedInvestigational

    Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase (RdRp) enzyme complex for genomic replication, which can be inhibited by a class of drugs known as nucleoside analogues.

  2. Drug

    Rintodestrant

    go.drugbank.com/drugs/DB21472
    Investigational

    Rintodestrant is under investigation in clinical trial NCT03455270 (G1T48, an Oral SERD, Alone and in Combination With Palbociclib in ER-Positive, HER2-Negative Advanced Breast Cancer).

  3. Drug

    Taragarestrant

    go.drugbank.com/drugs/DB21574
    Investigational

    Taragarestrant is under investigation in clinical trial NCT06954961 (A Study to Evaluate D-0502 in Subjects With ER+ Her2- Locally Advanced or Metastatic Breast Cancer).

  4. Drug

    Merimepodib

    go.drugbank.com/drugs/DB04862
    Investigational

    Merimepodib (VX-497) is a novel noncompetitive inhibitor of IMPDH.

  5. Drug

    Zinc glycinate

    go.drugbank.com/drugs/DB14493
    Investigational

    Glycoprotein marker of gastrointestinal cancer.

    Mixtures: Corvite FE, Corvite FE
  6. Drug

    Avatrombopag

    go.drugbank.com/drugs/DB11995
    ApprovedInvestigational

    This approval was supported by results from the AVA-PED-301 phase 3 study, which demonstrated durable platelet responses and favorable safety in children with persistent or chronic immune thrombocytopenia

  7. Drug

    Choriogonadotropin alfa

    go.drugbank.com/drugs/DB00097
    ApprovedInvestigational

    Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-1...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  8. Drug

    Magnesium hydroxide

    go.drugbank.com/drugs/DB09104
    ApprovedInvestigational

    Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium ...

    Mixtures: Diovol EX Tab, Sentriva-ESCategories: Genito Urinary System and Sex Hormones
  9. Drug

    Axicabtagene ciloleucel

    go.drugbank.com/drugs/DB13915
    ApprovedInvestigational

    Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-c...

    Categories: Complex Mixtures
  10. Target

    Tumor susceptibility gene 101 protein

    go.drugbank.com/bio_entities/BE0019070
    TargetHumans

    Component of the ESCRT-I complex, a regulator of vesicular trafficking process. … Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation.

    Synonyms: ESCRT-I complex subunit TSG101