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Dexrazoxane
go.drugbank.com/drugs/DB00380ApprovedInvestigationalWithdrawn[PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. … It appears to inhibit formation of a toxic iron-anthracycline complex.
Categories: Compounds used in a research, industrial, or household setting, Topoisomerase II InhibitorsRuxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigational[A229708] In 2014, it was approved for the treatment of polycythemia vera in adults who have an inadequate response to or are intolerant of [hydroxyurea] and in 2019, ruxolitinib was approved for use in … In phase II clinical trials, ruxolitinib improved chest computed tomography and improved recovery in patients with lymphopenia.
Tocofersolan
go.drugbank.com/drugs/DB11635ApprovedIn addition to the above, tocofersolan has been studied as a promising application as an absorption enhancer in drug delivery [MSDS]. … D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis [L2371].
Categories: Compounds used in a research, industrial, or household settingCetalkonium
go.drugbank.com/drugs/DB11583ApprovedWithdrawn[L2137] Cetalkonium is approved by the FDA for its use in over-the-counter products as a skin protectant.[L2737] By Health Canada, it is also approved for its use in over-the-counter products.[L1113] … Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Cetalkonium ionOlmesartan
go.drugbank.com/drugs/DB00275ApprovedInvestigationalIn particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. … [A175330] It was developed by Daiichi Sankyo Pharmaceuticals and approved in 2002.[A175345, L12882]
Categories: Angiotensin II receptor antagonists, Angiotensin II receptor blockers (ARBs), plainQuetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalInitially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. … It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189]
Products: FRENI-S IR, Q-PINNADH
go.drugbank.com/drugs/DB00157ApprovedNutraceuticalIt is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). … It forms NADP with the addition of a phosphate group to the 2' position of the adenosyl nucleotide through an ester linkage. (Dorland, 27th ed)
Mixtures: HEPASELAMİN AMİNOASİT IV İNFÜZYON ÇÖZELTİSİ 500 ML SETLİ ŞİŞE, HEPASELAMİN AMİNOASİT IV İNFÜZYON ÇÖZELTİSİ 500 ML SETSİZ ŞİŞEChlorine
go.drugbank.com/drugs/DB11109ApprovedInvestigationalIt was also used in chemical warfare and in rocket fuel. … Being a yellow-green gas at room temperature, chlorine is the second most abundant halogen on Earth. It is commonly used in sanitation, disinfection and antiseptic processes.
Mixtures: NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 2500 ML, NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 1870 MLCategories: Compounds used in a research, industrial, or household settingCarbamide peroxide
go.drugbank.com/drugs/DB11129ApprovedInvestigationalAs it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. … It is available in OTC otic drugs as non-water, non-oil-based solutions used to soften, loosen and remove excessive ear wax, or cerumen.
Categories: Compounds used in a research, industrial, or household settingVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalThe FDA said it is keeping the black box in place at least until the results of the trial are announced. … Pfizer is conducting an additional safety study of the drug, results of which are expected in late 2015.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine Dependence