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Tulmimetostat
go.drugbank.com/drugs/DB19446InvestigationalTulmimetostat is under investigation in clinical trial NCT05467748 (EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer).
Synonyms: (2R)-7-chloro-2-[trans-4-(3-methoxyazetidin-1-yl)cyclohexyl]-2,4-dimethyl-N-{[6-methyl-4-(methylsulfanyl)-2-oxo-1,2-dihydropyridin-3-yl]methyl}-2H-1,3-benzodioxole-5-carboxamide, 1,3-Benzodioxole-5-carboxamide, 7-chloro-N-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-[trans-4-(3-methoxy-1-azetidinyl)cyclohexyl]-2,4-dimethyl-, (2R)-CM4620
go.drugbank.com/drugs/DB16466InvestigationalCM4620 (Zegocractin), is under investigation in multiple clinical trials, including NCT04195347 (pancreatitis due to asparaginase), NCT03709342 (PK/PD study in acute pancreatitis), NCT03401190 and NCT04681066
Categories: Heterocyclic Compounds, 1-RingSynonyms: BENZAMIDE, N-(5-(6-CHLORO-2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)-2-PYRAZINYL)-2-FLUORO-6-METHYL-, N-(5-(6-CHLORO-2,2-DIFLUOROBENZO(D)(1,3)DIOXOL-5-YL)PYRAZIN-2-YL)-2-FLUORO-6-METHYLBENZAMIDEZelavespib
go.drugbank.com/drugs/DB12638InvestigationalZelavespib (PU-H71) has been used in trials studying the treatment of LYMPHOMA, Solid Tumors, Metastatic Solid Tumor, and Myeloproliferative Neoplasms (MPN).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 8-((6-Iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine, 9H-purine-9-propanamine, 6-amino-8-((6-iodo-1,3-benzodioxol-5-yl)thio)-N-(1-methylethyl)-Zabedosertib
go.drugbank.com/drugs/DB18767InvestigationalSynonyms: 2-pyridinecarboxamide, n-(6-(1-hydroxy-1-methylethyl)-2-(2-(methylsulfonyl)ethyl)-2h-indazol-5-yl)-6-(trifluoromethyl)-, N-(6-(1-hydroxy-1-methylethyl)-2-(2-(methylsulfonyl)ethyl)-2h-indazol-5-yl)-6-(trifluoromethyl)-2-pyridinecarboxamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime
go.drugbank.com/drugs/DB08010ExperimentalSynonyms: (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oximePyrrocaine
go.drugbank.com/drugs/DB20415ExperimentalPyrrocaine is a small molecule drug. The usage of the INN stem '-caine' in the name indicates that Pyrrocaine is a local anaesthetic. Pyrrocaine has a monoisotopic molecular weight of 232.16 Da.
Synonyms: 1-pyrrolidineaceto-2',6'-xylidide.Ethoxyquin
go.drugbank.com/drugs/DB16866ExperimentalSynonyms: 6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinolineCategories: Heterocyclic Compounds, 2-RingGB-115
go.drugbank.com/drugs/DB19204InvestigationalGB-115 is under investigation in clinical trial NCT05586789 (A Study of the Efficacy and Safety of Ranquilon Tablets in Patients With Anxiety in Neurasthenia and Adjustment Disorders).
Synonyms: L-tryptophanamide, n-(1-oxo-6-phenylhexyl)glycyl-, N-(1-oxo-6-phenylhexyl)glycyl-l-tryptophanamide2'-deoxythioguanosine
go.drugbank.com/drugs/DB18117ExperimentalCategories: Heterocyclic Compounds, 2-RingSynonyms: 2'-deoxy-6-thioguanosine, 2'-desoxy-6-thioguanosine2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID
go.drugbank.com/drugs/DB06907ExperimentalSynonyms: 2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID