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Fish oil
go.drugbank.com/drugs/DB13961ApprovedInvestigationalNutraceuticalFish oil is a component of SMOFLIPID, which was FDA approved in July 2016. … demonstrated abilities in minimizing or preventing hypertriglyceridemia when taken as an adjunct to a healthy diet [FDA Label].
Mixtures: SmofKabiven N-Plus zentral Emulsion zur Infusion, SmofKabiven N-Plus zentral elektrolytfrei Emulsion zur InfusionCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNonacog beta pegol
go.drugbank.com/drugs/DB13933ApprovedInvestigationalNonacog beta pegol is a recombinant coagulation factor IX derivative. … It is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Coagulation Factor IX (Recombinant), GlycoPEGylatedFamotidine
go.drugbank.com/drugs/DB00927ApprovedInvestigationalFamotidine is a competitive histamine-2 (H<sub>2</sub>) receptor antagonist that works to inhibit gastric acid secretion. … It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children.
Synonyms: N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide, 3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidineInternational brands: Mylanta AR, Sedanium-RNicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalNicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. … Nicotine is also important medically because of its presence in tobacco smoke.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceSynonyms: (S)-3-(N-methylpyrrolidin-2-yl)pyridine, 3-(2-(N-methylpyrrolidinyl))pyridinePhentermine
go.drugbank.com/drugs/DB00191ApprovedIllicitInvestigationalPhentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. … [A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to obtain the desired effect.[A174373]
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 SubstratesProducts: Phentermine HCl C-IV, Phentermine HCL C-IVRadium Ra 223 dichloride
go.drugbank.com/drugs/DB08913ApprovedInvestigationalRadium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short range but high linear energy alpha particles. … As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases.
Synonyms: Radium chloride Ra-223, Radium (Ra-223) dichlorideProducts: XOFIGO 1100 KBQ/ML IV ENJEKSIYON IÇIN ÇÖZELTI IÇEREN FLAKON,1 ADET, XOFIGO®Iloprost
go.drugbank.com/drugs/DB01088ApprovedInvestigational[A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47.[L50146] It is a potent vasodilator with reported anti-thrombotic properties. … Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived.
Synonyms: (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid, (E)-(3aS, 4R, 5R, 6aS)-hexahydro-5-hydroxy-4-[(E)-(3S,4RS) 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H),Δ-pentalenevaleric acidProducts: İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL, İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 AMPULValine--tRNA ligase
go.drugbank.com/bio_entities/BE0000223TargetEnzymeHumansCatalyzes the attachment of valine to tRNA(Val)
Polypeptides: Valine--tRNA ligasePolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429]. … Polymyxin B was discovered in the 1940s[A176429]. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes[A176426].
Synonyms: Polymyxin B, Polimixina BInternational brands: Polomyxin BArm Pain
go.drugbank.com/conditions/DBCOND0043272Drugs: MyrtecaineSynonyms: Pain in arm, Pain in upper limb