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Nicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalNicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. … Nicotine is also important medically because of its presence in tobacco smoke.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceSynonyms: (S)-3-(N-methylpyrrolidin-2-yl)pyridine, 3-(2-(N-methylpyrrolidinyl))pyridinePhentermine
go.drugbank.com/drugs/DB00191ApprovedIllicitInvestigationalPhentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. … [A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to obtain the desired effect.[A174373]
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 SubstratesProducts: Phentermine HCl C-IV, Phentermine HCL C-IVIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. … [A39076] On the available products, ibuprofen is administered as a racemic mixture.
Synonyms: (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid, (±)-2-(p-isobutylphenyl)propionic acidInternational brands: Act-3, Alges-XNicotinamide
go.drugbank.com/drugs/DB02701ApprovedInvestigationalAn important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. … Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Synonyms: 3-pyridinecarboxamide, β-pyridinecarboxamideMixtures: Cellmov Cell Line Mask, Too im Cell ALL IN ONERadium Ra 223 dichloride
go.drugbank.com/drugs/DB08913ApprovedInvestigationalRadium Ra 223 Dichloride is a radiopharmaceutical containing the radioisotope radium-223 that emits short range but high linear energy alpha particles. … As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases.
Synonyms: Radium chloride Ra-223, Radium (Ra-223) dichlorideProducts: XOFIGO 1100 KBQ/ML IV ENJEKSIYON IÇIN ÇÖZELTI IÇEREN FLAKON,1 ADET, XOFIGO®Iloprost
go.drugbank.com/drugs/DB01088ApprovedInvestigational[A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47.[L50146] It is a potent vasodilator with reported anti-thrombotic properties. … Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived.
Synonyms: (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid, (E)-(3aS, 4R, 5R, 6aS)-hexahydro-5-hydroxy-4-[(E)-(3S,4RS) 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H),Δ-pentalenevaleric acidProducts: İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL, İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 AMPULValine--tRNA ligase
go.drugbank.com/bio_entities/BE0000223TargetEnzymeHumansCatalyzes the attachment of valine to tRNA(Val)
Polypeptides: Valine--tRNA ligaseKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Mixtures: Ixoba M, VOYDOL-CCategories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDSArm Pain
go.drugbank.com/conditions/DBCOND0043272Drugs: MyrtecaineSynonyms: Pain in arm, Pain in upper limbArsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalArsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. … In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: TRISENOX 1 MG/1 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 ADET, LEUSENOX 10 MG/10 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 1 ADET