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Vasopressin
go.drugbank.com/drugs/DB00067ApprovedInvestigationalVasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation … [A228013] It is currently marketed under the trademark VASOSTRICT® by PAR Pharmaceuticals.[L31413]
Rofecoxib
go.drugbank.com/drugs/DB00533ApprovedWithdrawnThe introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras.
Flupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnIt is used for the management of chronic schizophrenia in patients whose main manifestations do not include excitement, agitation or hyperactivity. … It is approved for use in Canada and other countries around the world, but not in the US.
Tiludronic acid
go.drugbank.com/drugs/DB01133ApprovedVet approvedWithdrawnTiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to [etidronic acid] and [clodronic acid]. … [A1923] Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone.[A202235] Tiludronic acid was granted FDA approval on 7 March 1997.[L4763]
Categories: Drugs for Treatment of Bone Diseases, Phospholipases A, antagonists & inhibitorsBrexpiprazole
go.drugbank.com/drugs/DB09128ApprovedInvestigationalIt has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. … Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM).
Categories: Antidepressive Agents Indicated for DepressionSynonyms: Lu-AF41156Cipaglucosidase alfa
go.drugbank.com/drugs/DB16708ApprovedInvestigationalCipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized … by a deficiency in GAA.
Synonyms: Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphateSucralfate
go.drugbank.com/drugs/DB00364ApprovedInvestigationalIt was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form [L6073, L6076]. … Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Fluocinolone acetonide
go.drugbank.com/drugs/DB00591ApprovedInvestigationalVet approvedFluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity. … [T357] It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices.
Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseProbenecid
go.drugbank.com/drugs/DB01032ApprovedInvestigationalThe prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubu...
Mixtures: Pro Biosan KitCategories: Compounds used in a research, industrial, or household settingChloramphenicol
go.drugbank.com/drugs/DB00446ApprovedInvestigationalVet approvedWithdrawnIt has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic.
Mixtures: Actinac PwrCategories: Antibiotics for Topical Use, Antibacterials for Systemic Use