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Ozanimod
go.drugbank.com/drugs/DB12612ApprovedInvestigationalIt was developed by Celgene (now acquired by Bristol-Myers Squibb) [L11025] and was approved by the FDA on March 26, 2020. … [A176474] Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting.
Fostemsavir
go.drugbank.com/drugs/DB11796ApprovedInvestigational[A215057] Fostemavir is the first attachment inhibitor to receive FDA approval, granted in July 2020 for use in combination with other antiretrovirals in highly treatment-experienced patients with multidrug-resistant
Tinzaparin
go.drugbank.com/drugs/DB06822ApprovedInvestigationalLMWHs are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin. … It is an anticoagulant and considered an antithrombotic. Tinzaparin must be given either subcutaneously or parenterally.
Products: INNOHEP (20,000 IU/ML), INNOHEP (10,000 IU/ML)Ethinylestradiol
go.drugbank.com/drugs/DB00977ApprovedInvestigational[A191107] Ethinylestradiol was granted FDA approval on 25 June 1943.[L11884] … [A191107] It was developed in an effort to create an estrogen with greater oral bioavailability.
Mixtures: ACTIVA DE +TABLETAS RECUBIERTAS, ADELLA MINI TABLETA CON RECUBRIMIENTO DE GELATINAFosfomycin
go.drugbank.com/drugs/DB00828ApprovedInvestigational[A230348] In terms of chemical structure, fosfomycin is a phosphoenolpyruvate analog and contains a phosphonic group and an epoxide ring. … [A230378] Despite being FDA approved only for urinary tract infections, fosfomycin actually has a broad spectrum of activity and is active against both gram-positive and gram-negative bacteria.
Products: FOSFOCIL GU, FOSFOMICINA MYLAN GENERICSFosinopril
go.drugbank.com/drugs/DB00492ApprovedInvestigationalFosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals
Mixtures: FOSINOPRIL E IDROCLOROTIAZIDE DOC GENERICI, FOSINOPRIL E IDROCLOROTIAZIDE DOC GENERICIProducts: Nu-fosinopril, Ran-fosinoprilOxethazaine
go.drugbank.com/drugs/DB12532ApprovedWithdrawnIts actions have shown to relieve dysphagia, relieve pain due to reflux, chronic gastritis, and duodenal ulcer. … [A33104] Oxetacaine is approved by Health Canada since 1995 for its use as an antacid combination in over-the-counter preparations.
Pipendoxifene
go.drugbank.com/drugs/DB05414InvestigationalER modulator, ERA-923(Pipendoxifene) is a estrogen receptor modulator being evaluated for the treatment of breast cancer. … Pipendoxifene is a new 2-phenyl indole selective estrogen receptor modulators (SERM )that exhibits an excellent preclinical pharmacological profile and was selected for further development as a treatment
Abaloparatide
go.drugbank.com/drugs/DB05084ApprovedInvestigational[L740] It was first approved by the FDA on April 28, 2017,[A256748] for the treatment of osteoporosis in postmenopausal women and is also used to increase bone density in men with osteoporosis. … Abaloparatide is an N-terminal analog of parathyroid hormone-related protein (PTHrP) [A256778] and an agonist at the parathyroid hormone type 1 (PTH1) receptor.
Marnetegragene autotemcel
go.drugbank.com/drugs/DB17595Approved[L56115, L56116] Marnetegragene autotemcel is indicated for pediatric patients with severe LAD-I lacking an available HLA-matched sibling donor.[L56115] … [L56116, A275467] Marnetegragene autotemcel, also known as marne-cel, is an autologous hematopoietic stem cell-based gene therapy created from the patient's own hematopoietic stem cells.