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Displaying results 1461 - 1470 of 10000 in total
  1. Drug

    Atrasentan

    go.drugbank.com/drugs/DB06199
    ApprovedInvestigational

    [L52855] In April 2025, atrasentan was granted accelerated approval by the FDA for the reduction of proteinuria in patients with primary IgA nephropathy, becoming the first endothelin A receptor antagonist

  2. Drug

    Sodium lauryl sulfate

    go.drugbank.com/drugs/DB00815
    Approved

    It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity. … SLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Calcium polycarbophil

    go.drugbank.com/drugs/DB14684
    Approved

    Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali. … Based on its chemical structure, it is a synthetic polymer of polyacrylic acid cross-linked with divinyl glycol presenting a calcium atom as a counter-ion.

    Categories: Compounds used in a research, industrial, or household settingProducts: Fiber-ON-tablet
  4. Drug

    Evening primrose oil

    go.drugbank.com/drugs/DB11358
    ApprovedNutraceutical

    In its composition it presents some fatty acids such as [DB00132] and [DB13854]. … [L2845] By Health Canada, evening primrose oil is approved in over-the-counter combination dietary supplements.[L1113] By the EMA, evening primrose oil is approved in herbal preparations.[L2851]

    Mixtures: PRIM E CAPSULE, Evening Primrose Oil With Vitamin ECategories: Complex Mixtures
  5. Drug

    Niraparib

    go.drugbank.com/drugs/DB11793
    ApprovedInvestigational

    [L43277] Niraparib was approved by the European Commission on November 16, 2017 [L43742] and by Health Canada on June 27, 2019. … Niraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells.

  6. Drug

    Aspergillus fumigatus

    go.drugbank.com/drugs/DB10425
    Approved

    Aspergillus fumigatus extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  7. Drug

    Cochliobolus sativus

    go.drugbank.com/drugs/DB10433
    Approved

    Cochliobolus sativus extract is used in allergenic testing.

    Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture
  8. Drug

    Guanethidine

    go.drugbank.com/drugs/DB01170
    ApprovedWithdrawn

    An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. … It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.

    Synonyms: 2-(1-N,N-Heptamethyleneimino)ethylguanidine, N-(2-Perhydroazocin-1-ylethyl)guanidine
  9. Drug

    Dupilumab

    go.drugbank.com/drugs/DB12159
    ApprovedInvestigational

    It was first approved by the FDA in 2017. … It is currently used to treat atopic dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and eosinophilic esophagitis.

    Products: Dupixent 300 mg Solution for Injection in Pre-filled Syringe, Dupixent 200mg Solution for Injection in Pre-Filled Syringe
  10. Drug

    Nicotine

    go.drugbank.com/drugs/DB00184
    ApprovedInvestigational

    Nicotine is also important medically because of its presence in tobacco smoke.

    Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceSynonyms: 3-(N-methylpyrollidino)pyridine, 3-(2-(N-methylpyrrolidinyl))pyridine