Search
Formestane
go.drugbank.com/drugs/DB08905ApprovedWithdrawnSome clinical data has suggested that the clinically recommended dose of 250mg was too low. … It is not US FDA approved, and the intramuscular injection form of formestane (Lentaron) which was approved in Europe has been withdrawn.
19-norandrostenedione
go.drugbank.com/drugs/DB01434ExperimentalIllicitAfter 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned from use in competitive sports by the World Anti-Doping Agency. … In the body 19-norandrostenedione is rapidly metabolized into [nandrolone], also known as nortestosterone.
Carbamoylcholine
go.drugbank.com/drugs/DB00411Approved[A226315] Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and other parasympathetic effects. … Carbamoylcholine was granted FDA approval on 28 September 1972.[L30245]
Givinostat
go.drugbank.com/drugs/DB12645ApprovedInvestigationalIt has been investigated as a treatment for a variety of inflammatory diseases, like Crohn's disease and juvenile idiopathic arthritis, cancers like leukemia and lymphoma, as well as several muscular dystrophies … [L50316,A263446] Givinostat was granted FDA approval in March 2024 for the treatment of patients ≥6 years of age with Duchenne muscular dystrophy (DMD).
Mosunetuzumab
go.drugbank.com/drugs/DB15434ApprovedInvestigational[A249320,A249390] Mosunetuzumab has the potential to circumvent resistance to [rituximab] in patients with follicular lymphoma,[A249320,L42230] and unlike CAR-T therapies such as [axicabtagene ciloleucel … [L44562] and in December 2025, the subcutaneous formulation was approved for the same indication. [L54848]
Drospirenone
go.drugbank.com/drugs/DB01395ApprovedInvestigational[L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol] as an oral contraceptive therapy. … In its statement, the FDA has mentioned that increased risk of venous thromboembolism with oral contraceptives such as drospirenone exists but remains lower than the risk of this condition during pregnancy
Idelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalTreatment of lymphoma cells with idelalisib has been shown to result in inhibition of chemotaxis and adhesion, and reduced cell viability. … More specifically, idelalisib targets P110δ, the delta isoform of the enzyme phosphatidylinositol-4,5-bisphosphate 3-kinase, also known as PI-3K.
Polyethylene glycol 300
go.drugbank.com/drugs/DB11161ApprovedThey serve as solubilizers, excipients, lubricants, and chemical reagents. Low molecular weight glycols are observed to exhibit antibacterial properties as well. … PEG 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes.
Carprofen
go.drugbank.com/drugs/DB00821ApprovedVet approvedWithdrawnCarprofen was previously used in human medicine for over 10 years (1985-1995). … It was generally well tolerated, with the majority of adverse effects being mild, such as gastro-intestinal pain and nausea, similar to those recorded with aspirin and other non-steroidal anti-inflammatory
Esketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigational[L5596,A175462] On March 5, 2019, the nasal spray drug, _esketamine_, also known as _Spravato_ (by Janssen Pharmaceuticals), was approved by the FDA for treatment-resistant major depression. … This is the first time that the FDA has approved esketamine for any use. The FDA approved ketamine (Ketalar) in 1970.