19-Norandrostenedione refers to two steroid isomers that were once marketed as dietary supplements and mainly used by body builders. After 2005, 19-Norandrostenedione was regulated in the United States as a... After 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned from use in competitive sports by the World Anti-Doping Agency.
- Mechanism
- Curator reviewed
19-Norandrostenedione may be metabolized to 19-nortestosterone in both men and women. 19-Norandrostenedione, also known as nandrolone, is the basic substance of some very popular injectable anabolic steroids, however 19-norandrostenedione is not metabolized to testosterone. Whether or not increases in 19-nortestosterone levels would be sustained long enough by taking 19-norandrostenedione to show an increase in nitrogen retention and muscle strength and mass is unknown.
19-Norandrostenedione has also been shown to bind to androgen receptors with high selectivity. Transactivation of androgen receptor dependent reporter gene expression was 10 times lower than that produced by dihydrotestosterone.
- Primary indication
- The claim that supplemental 19-norandrostenedione has anabolic effects is unsubstantiated.Curator reviewed
- Formula / weight
- C18H24O2 · 272.382 g/mol (avg)
- Code names
- NSC-12164
Resolves to
JRIZOGLBRPZBLQ-QXUSFIETSA-NSMILES[H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H]What you can answer from here — as of September 19, 2026
Which companies are running trials of 19-norandrostenedione, in which indications and phases, and which of those programs are still active?
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