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Displaying results 1471 - 1480 of 10000 in total
  1. Drug

    Pegaspargase

    go.drugbank.com/drugs/DB00059
    ApprovedInvestigational

    [A103,A255912,L44667] Pegaspargase has the same mechanism of action as [L-asparaginase] derived from _Escherichia coli_, a previously developed enzyme used for the treatment of acute lymphoblastic … [A255912,A255917] In February 1994, pegaspargase was approved by the FDA for the treatment of ALL in patients with hypersensitivity to native forms of L-asparaginase.[A255927]

    Categories: Compounds used in a research, industrial, or household settingSynonyms: PEG-L-Asparaginase, Peg/L-asparaginase
  2. Drug

    Vildagliptin

    go.drugbank.com/drugs/DB04876
    ApprovedInvestigational

    , or a thiazolidinedione in patients with inadequate glycemic control following monotherapy. … [A232488] Oral vildagliptin was approved by the European Medicines Agency in 2008 for the treatment of type II diabetes mellitus in adults as monotherapy or in combination with [metformin], a sulfonylurea

    Mixtures: Vildagliptin/Metformin 1A Pharma 50 mg/850 mg – Filmtabletten, Vildagliptin/Metformin 1A Pharma 50 mg/1000 mg - FilmtablettenProducts: Vildagliptin 1A Pharma 50 mg - Tabletten
  3. Drug

    Brexpiprazole

    go.drugbank.com/drugs/DB09128
    ApprovedInvestigational

    It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. … Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM).

    Categories: Antidepressive Agents Indicated for DepressionSynonyms: Lu-AF41156
  4. Drug

    Flupentixol

    go.drugbank.com/drugs/DB00875
    ApprovedInvestigationalWithdrawn

    It is used for the management of chronic schizophrenia in patients whose main manifestations do not include excitement, agitation or hyperactivity. … It is approved for use in Canada and other countries around the world, but not in the US.

  5. Drug

    Afamitresgene autoleucel

    go.drugbank.com/drugs/DB18592
    ApprovedInvestigational

    self-inactivating lentiviral vector (LV) expressing an affinity-enhanced T cell receptor (TCR) specific for the human MAGE-A4. … LV containing the MAGE-A4 TCR transgene.

    Synonyms: HUMAN MELANOMA ANTIGEN A4 (MAGE FAMILY MEMBER A4, A, AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE
  6. Drug

    Follitropin

    go.drugbank.com/drugs/DB00066
    ApprovedInvestigational

    Follitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF). … However, a more recent study showed there is may be a slight clinical difference, with the alpha form tending towards a higher pregnancy rate and the beta form tending towards a lower pregnancy rate, but

    Mixtures: Pergoveris 150IU/75IU powder and solvent for solution for injection, MENOGON 75 IU Powder and Solvent for solution for InjectionSynonyms: FSH-a
  7. Drug

    Ethanolamine oleate

    go.drugbank.com/drugs/DB06689
    Approved

    Ethanolamine oleate is a mild sclerosing agent. … It is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate.

    Categories: Compounds used in a research, industrial, or household setting, Sclerosing Agents for Local Injection
  8. Drug

    Rofecoxib

    go.drugbank.com/drugs/DB00533
    ApprovedWithdrawn

    The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras.

  9. Drug

    (+)-menthol

    go.drugbank.com/drugs/DB11344
    Approved

    Mixtures: DR JOE LAB PMS Menstrual Pain Relief Cream DR JOE LAB, DR JOE LAB PMS Menstrual Pain Relief Cream DR JOE LAB
  10. Drug

    Chlorphenoxamine

    go.drugbank.com/drugs/DB09007
    ApprovedWithdrawn

    It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.

    Categories: Antihistamines for Topical Use, Antihistamines for Systemic Use