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Displaying results 141 - 150 of 162531 in total
  1. Drug

    Cobicistat

    go.drugbank.com/drugs/DB09065
    ApprovedInvestigational

    Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile. … Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered

    Synonyms: 1,3-thiazol-5-ylmethyl [(2R,5R)-5-{[(2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamateMixtures: PREZCOBIX® TABLETAS RECUBIERTAS, GENVOYA ® TABLETAS RECUBIERTAS
  2. Drug

    2'-Monophosphoadenosine-5'-Diphosphoribose

    go.drugbank.com/drugs/DB04497
    Experimental

    Synonyms: 2'-Monophosphoadenosine-5'-Diphosphoribose
  3. Drug

    2'-Deoxyguanosine-5'-Triphosphate

    go.drugbank.com/drugs/DB02181
    Experimental

    Synonyms: 2'-Deoxyguanosine-5'-Triphosphate
  4. Drug

    2'-Monophosphoadenosine-5'-Diphosphate

    go.drugbank.com/drugs/DB02363
    Experimental

    Synonyms: 2'-Monophosphoadenosine-5'-Diphosphate
  5. Drug

    5-methyl-2'-deoxypseudouridine

    go.drugbank.com/drugs/DB03763
    Experimental

    Synonyms: 5-methyl-2'-deoxypseudouridine
  6. Drug

    2'-Deoxyguanosine-5'-Monophosphate

    go.drugbank.com/drugs/DB04457
    Experimental

    Synonyms: 2'-Deoxyguanosine-5'-Monophosphate
  7. Drug

    2'-Deoxyguanosine-5'-Diphosphate

    go.drugbank.com/drugs/DB03491
    Experimental

    Synonyms: 2'-Deoxyguanosine-5'-Diphosphate
  8. Drug

    Cladribine

    go.drugbank.com/drugs/DB00242
    ApprovedInvestigational

    Cladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes. … [A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell

    Categories: 2-Chloroadenosine, Heterocyclic Compounds, 2-RingSynonyms: 2-chloro-6-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine, (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
  9. Drug

    Azaribine

    go.drugbank.com/drugs/DB19364
    ApprovedWithdrawn

    Synonyms: 2-.beta.-d-ribofuranosyl-as-triazine-3,5(2h,4h)-dione 2',3',5'-triacetate, 6-azauridine 2',3',5'-triacetateCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Milrinone

    go.drugbank.com/drugs/DB00235
    ApprovedInvestigational

    Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. … [A228323] Milrinone is a second-generation bipyridine phosphodiesterase (PDE) inhibitor created through chemical modification of [amrinone].

    Synonyms: 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrileCategories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 3 Inhibitors