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Necitumumab
go.drugbank.com/drugs/DB09559ApprovedInvestigationalWithdrawnNecitumumab is approved for use in combination with cisplatin and gemcitabine as a first-line treatment for metastatic squamous non-small cell lung cancer (NSCLC). … It functions by binding to epidermal growth factor receptor (EGFR) and prevents binding of its ligands, a process that is involved in cell proliferation, metastasis, angiogenesis, and malignant progression
Categories: Epidermal Growth Factor Receptor Antagonist, EGFR (Epidermal Growth Factor Receptor) inhibitorsProducts: PORTRAZZA CONCENTRATE FOR SOLUTION FOR INFUSION 800MG/50MLTocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigationalTocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions.
Categories: Biologics for Rheumatoid Arthritis Treatment, Experimental Unapproved Treatments for COVID-19Products: Actemra Concentrate for Solution for Infusion 20mg/ml, ACTEMRA 20 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION.Elosulfase alfa
go.drugbank.com/drugs/DB09051ApprovedInvestigationalIt was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™.
Products: Vimizim 1mg/ml Concentrate for Solution for InfusionOfatumumab
go.drugbank.com/drugs/DB06650ApprovedInvestigationalIn February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing Authorization Application (MAA), respectively, for ofatumumab for the treatment of RMS in adults. … [A6921] Ofatumumab is available for intravenous administration and is marketed as Arzerra.
Products: KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML, Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringeSiltuximab
go.drugbank.com/drugs/DB09036ApprovedInvestigationalIts use is indicated for the treatment of adult patients with multicentric Castleman's disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative.
Products: Sylvant 400mg Powder for Concentrate for Solution for Infusion, Sylvant 100mg Powder for Concentrate for Solution for InfusionDalbavancin
go.drugbank.com/drugs/DB06219ApprovedInvestigationalModifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin but with increased activity and once-weekly dosing [FDA Label, F2356, A4072, A4073]. … Its use is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by the following gram-positive microorganisms: Staphylococcus aureus (including methicillin-susceptible
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Dalbavancin Accord 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Dalbavancin ratiopharm 500 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungInsulin aspart
go.drugbank.com/drugs/DB01306ApprovedInvestigationalAbsorption of glucose into cells allows for its transformation into glycogen or fat for storage. … Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Mixtures: Ryzodeg® FlexTouch® 100 U/ml Solution for InjectionCategories: Insulins and Analogues for Injection, Fast-ActingInsulin degludec
go.drugbank.com/drugs/DB09564ApprovedInvestigational[A18561,A18562,A18563,A18564,A174934] Absorption of glucose into cells allows for its transformation into glycogen or fat for storage. … Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Mixtures: Ryzodeg® FlexTouch® 100 U/ml Solution for InjectionProducts: Tresiba® FlexTouch® 100 U/ml Solution for Injection, Tresiba ® FlexTouch® 100 U/ml Solution for InjectionAtosiban
go.drugbank.com/drugs/DB09059ApprovedInvestigationalAtosiban is licensed in proprietary and generic forms for the delay of imminent pre-term birth in pregnant adult women.
Products: TRACTOCILE 7.5MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION, TRACTOCILE (7.5 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION)Rituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalFDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for a variety of conditions [FDA label].
Categories: Biologics for Rheumatoid Arthritis TreatmentProducts: Mabthera Concentrate for Solution for Infusion 100mg/10ml, TRUXIMA® CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/ML