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Chamomile
go.drugbank.com/drugs/DB14357ApprovedChamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Chamomile Flower (Hungarian or German), Matricaria Recutita L. FlowerProducts: Soulagement De L'indigestionCaspofungin
go.drugbank.com/drugs/DB00520ApprovedInvestigationalIt is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans, -3-hydroxy-L-proline cyclic (6-1)-peptideSincalide
go.drugbank.com/drugs/DB09142ApprovedSincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders. … The evacuation of bile that results is similar to that which occurs physiologically in response to endogenous cholecystokinin.
Synonyms: CCK-8, CCK C-terminal octapeptideProducts: Kinevac Pws Inj 5mcg/vialFexofenadine
go.drugbank.com/drugs/DB00950ApprovedInvestigationalFexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. … [L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation
Mixtures: ALERMED® D, Allegra D-12 HourCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingAurothioglucose
go.drugbank.com/drugs/DB09121ApprovedWithdrawnContemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis [A32326]. … Many if not most gold compounds that were indicated for rheumatoid arthritis therapy have since been replaced with the use of various current disease modifying anti-rheumatic drugs (DMARDs) like methotrexate
International brands: Solganal BProducts: Solganal Inj 50mg/mlPizotifen
go.drugbank.com/drugs/DB06153ApprovedSandomigran is available in a number of countries but is not approved by the FDA nor EMA. … Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Heterocyclic Compounds, 1-RingProducts: Sandomigran DSTafluprost
go.drugbank.com/drugs/DB08819ApprovedChemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.
Mixtures: TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container, Taptiqom 15 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisProducts: Saflutan 15 Mikrogramm/ml Augentropfen im Einzeldosisbehältnis, SAFLUTAN®Reviparin
go.drugbank.com/drugs/DB09259Approved[A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation by the FDA.[L1469] … [A32019] It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa.
Products: CLIVARIN 5726 IE A XA/ML, CLIVARODI 17178 A XA/MLVindesine
go.drugbank.com/drugs/DB00309ApprovedInvestigationalWithdrawnVindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine, 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastineBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approvedBetamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. … [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders.
Mixtures: GENTAMICINA E BETAMETASONE DOC GENERICI, GENTAMICINA E BETAMETASONE MYLAN GENERICSCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, P-glycoprotein substrates