Tafluprost

DB08819ApprovedSmall moleculeProstaglandins, Synthetic

Tafluprost is an ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma. A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

Chemical structure of Tafluprost
Mechanism
Curator reviewed
Primary indication
Tafluprost is indicated for reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.Curator reviewed · 4 structured indications
Formula / weight
C25H34F2O5 · 452.5313 g/mol (avg)
First approval
Canada, 2016 · United States, 2012
Code names
AFP-168 · MK-2452
Brand names
  • Zioptan

Resolves to

Compound
UNII1O6WQ6T7G3CAS209860-87-7ChEMBLCHEMBL1963683ChEBI66899PubChem9868491KEGGD06274
Clinical / RWD
RxNorm1244607ATCS01EE05PharmGKBPA165958432
Structure
InChIKeyWSNODXPBBALQOF-VEJSHDCNSA-NSMILESCC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(F)(F)COC1=CC=CC=C1
Targets
P43088PTGFR

What you can answer from here — as of September 14, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
107Drug interactionsStructured to mechanism, not free text
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24Clinical trialsPhase, status and sponsor resolved per trial
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4Structured indicationsCondition, population, route and combination as fields, not prose
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1ContraindicationEach with its own population and attribute set
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63Marketed productsAcross 11 countries and 16 labellers
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1ATC codeIncluding every combination product, plus 16 drug categories
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8+ReferencesStructured and connected to the statements they support
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