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Olmesartan
go.drugbank.com/drugs/DB00275ApprovedInvestigationalIn particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. … [A175330] It was developed by Daiichi Sankyo Pharmaceuticals and approved in 2002.[A175345, L12882]
Categories: Angiotensin II receptor antagonists, Angiotensin II receptor blockers (ARBs), plainQuetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalInitially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. … It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189]
Products: FRENI-S IR, Q-PINDexrazoxane
go.drugbank.com/drugs/DB00380ApprovedInvestigationalWithdrawn[PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. … It appears to inhibit formation of a toxic iron-anthracycline complex.
Categories: Compounds used in a research, industrial, or household setting, Topoisomerase II InhibitorsChlorine
go.drugbank.com/drugs/DB11109ApprovedInvestigationalIt was also used in chemical warfare and in rocket fuel. … Being a yellow-green gas at room temperature, chlorine is the second most abundant halogen on Earth. It is commonly used in sanitation, disinfection and antiseptic processes.
Mixtures: NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 2500 ML, NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 1870 MLCategories: Compounds used in a research, industrial, or household settingVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalThe FDA said it is keeping the black box in place at least until the results of the trial are announced. … Pfizer is conducting an additional safety study of the drug, results of which are expected in late 2015.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceDifenoxin
go.drugbank.com/drugs/DB01501ApprovedIllicitDifenoxin is an active metabolite of the anti-diarrheal drug, diphenoxylate, which is also used in combination with atropine in the brand mixture Lomotil(R). … It works mostly in the periphery and activates opioid receptors in the intestine rather than the central nervous system (CNS). [3] Difenoxin is also closely related to loperamide, but unlike loperamide
Berdazimer
go.drugbank.com/drugs/DB18712Approved[A262965] Previously, the first line treatment for molluscum contagiosum was surgical excision, although it poses challenges such as repeated doctor visits, post-surgical scarring and skin discoloration … It is one of the 5 most prevalent skin diseases in the world and the third-most common viral skin infection in children.
Carbamide peroxide
go.drugbank.com/drugs/DB11129ApprovedInvestigationalAs it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. … It is available in OTC otic drugs as non-water, non-oil-based solutions used to soften, loosen and remove excessive ear wax, or cerumen.
Categories: Compounds used in a research, industrial, or household settingBrexanolone
go.drugbank.com/drugs/DB11859ApprovedInvestigationalprimary endpoints that compare success in the weaning of third-line agents and resolution of potentially life-threatening status epilepticus with brexanolone vs. placebo when added to standard-of-care … In particular, the use of brexanolone in treating PPD is surrounded with promise because it acts in part as a synthetic supplement for possible deficiencies in endogenous brexanolone (allopregnanolone)
Cantharidin
go.drugbank.com/drugs/DB12328ApprovedInvestigationalinflammatory model or in cancer treatment. … Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that is produced as an oral fluid in the alimentary canal of the male blister beetle.
Categories: Compounds used in a research, industrial, or household setting