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Megestrol acetate
go.drugbank.com/drugs/DB00351ApprovedInvestigationalVet approved17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. … As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Synonyms: MGA, 17α-Acetoxy-6-dehydro-6-methylprogesteroneCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCiticoline
go.drugbank.com/drugs/DB12153ApprovedInvestigationalWithdrawnCiticoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides.
Synonyms: Cytidine 5'-diphosphocholine, Cytidine-5'-diphosphocholineCategories: Heterocyclic Compounds, 1-RingCanagliflozin
go.drugbank.com/drugs/DB08907ApprovedInvestigationalCanagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise … It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 for a second indication of reducing the risk of cardiovascular events in patients diagnosed with type
Mixtures: VOKANAMET ® TM_TABLETAS RECUBIERTAS 150/1000 MG, VOKANAMET 150 MG/500 MGCategories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. … Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.
Synonyms: (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol, (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanolMixtures: CONCOR ® AM 5 MG / 10 MG, CONCOR ® AM 5 MG / 10 MGMifepristone
go.drugbank.com/drugs/DB00834ApprovedInvestigationalMifepristone is a progestational and glucocorticoid hormone antagonist. … As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: MIFEPRISTONA 200 MG, MIFEPRISTONE 200 MGFlumazenil
go.drugbank.com/drugs/DB01205ApprovedInvestigationalFumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingProducts: ANESED-R 1 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, ANTİZEPİN 1 MG/10 ML İ.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADETPyrazinamide
go.drugbank.com/drugs/DB00339ApprovedInvestigationalA pyrazine that is used therapeutically as an antitubercular agent.
Synonyms: 2-carbamylpyrazine, 2-pyrazinecarboxamideMixtures: RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG, RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MGMinoxidil
go.drugbank.com/drugs/DB00350ApprovedInvestigationalA potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Synonyms: 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide, 2,4-Diamino-6-piperidinopyrimidine 3-oxideMixtures: MINOXIDIL 7% / NIACINAMIDE 4% s, FluMisch 5% MinoxidilSelegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease.
Synonyms: L-DeprenalinCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Compounds used in a research, industrial, or household settingDalfampridine
go.drugbank.com/drugs/DB06637ApprovedInvestigationalDalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. … FDA approved on January 22, 2010.
Synonyms: 4-AP, 4-AminopyridineCategories: Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index, OCT2 Substrates with a Narrow Therapeutic Index