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Displaying results 1531 - 1540 of 3181 in total
  1. Drug

    Trastuzumab deruxtecan

    go.drugbank.com/drugs/DB14962
    ApprovedInvestigational

    Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. It is classified as an antibody-drug conjugate. The cleavabl...

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  2. Drug

    JNJ-55308942

    go.drugbank.com/drugs/DB19110
    Investigational

    JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).

    Categories: Purinergic P2 Receptor Antagonists
  3. Drug

    Vipadenant

    go.drugbank.com/drugs/DB06625
    Investigational

    Categories: Purinergic P1 Receptor Antagonists
  4. Drug

    LJ-2698

    go.drugbank.com/drugs/DB18018
    Experimental

    Categories: Purinergic P1 Receptor Antagonists
  5. Drug

    Naxifylline

    go.drugbank.com/drugs/DB06471
    Experimental

    Categories: Purinergic P1 Receptor Antagonists
  6. Drug

    DPCPX

    go.drugbank.com/drugs/DB12946
    Investigational

    CPX has been used in trials studying the treatment of Cystic Fibrosis.

    Categories: Purinergic P1 Receptor Antagonists
  7. Drug

    Binodenoson

    go.drugbank.com/drugs/DB04853
    Investigational

    Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor. This specificity allows Binodenoson to deliver - in a single injection - a more effective d...

    Categories: Purinergic P1 Receptor Agonists
  8. Drug

    Istradefylline

    go.drugbank.com/drugs/DB11757
    ApprovedInvestigational

    Istradefylline, or KW6002, was developed by Kyowa Hakko Kirin in Japan for the treatment of Parkinson's disease as an adjunct to standard therapy. Unlike standard dopaminergic therapies for Parkinson's, Istradefylline targets adenosine A...

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  9. Drug

    Vitamin A

    go.drugbank.com/drugs/DB00162
    ApprovedInvestigationalNutraceuticalVet approved

    Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A i...

    Mixtures: Ch-P Cap, P-NATAL®Products: VIT A N
  10. Drug

    Tecadenoson

    go.drugbank.com/drugs/DB04954
    Investigational

    Tecadenoson is a novel selective A1 adenosine receptor agonist that is currently being evaluated for the conversion of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm. It is being developed by CV Therapeutics, Inc.

    Categories: Purinergic P1 Receptor Agonists