Search

Displaying results 1551 - 1560 of 10000 in total
  1. Drug

    Somapacitan

    go.drugbank.com/drugs/DB15093
    ApprovedInvestigational

    [A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effect so that it requires weekly dosing rather than daily. … [A219146] Somapacitan was granted FDA approval on 28 August 2020.[L15666]

  2. Drug

    Iptacopan

    go.drugbank.com/drugs/DB16200
    ApprovedInvestigational

    [A262566] Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. … This approval was based on favorable results obtained from the phase III APPL-PNH and APPOINT-PNH studies, where 82.3% and 77.5% of patients experienced a sustained hemoglobin improvement without transfusions

    Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of Chemicals
  3. Drug

    Sipavibart

    go.drugbank.com/drugs/DB21908
    ApprovedInvestigational

    Sipavibart is a recombinant human IgG1 monoclonal antibody that is long-acting. … [A274088] Sipavibart is approved for the pre-exposure prophylaxis treatment of COVID-19 in immunocompromised patients.[L53418]

  4. Drug

    rdESAT-6

    go.drugbank.com/drugs/DB21906
    Approved

    rdESAT-6 is a recombinant dimer of _Mycobacterium tuberculosis_ early secretory antigenic target used as an ingredient in the diagnostic agent SIILTIBCY along with [rCFP-10].[L53638]

  5. Drug

    Guanabenz

    go.drugbank.com/drugs/DB00629
    ApprovedWithdrawn

    Guanabenz is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.

  6. Drug

    Methyldopa

    go.drugbank.com/drugs/DB00968
    ApprovedInvestigational

    Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. … [A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form.

    International brands: Nu-MedopaProducts: Nu-medopa Tab 250mg, Nu-medopa Tab 500mg
  7. Drug

    Atracurium besylate

    go.drugbank.com/drugs/DB00732
    Approved

    A non-depolarizing neuromuscular blocking agent with short duration of action. … Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents

    Synonyms: Besilato de atracurio
  8. Drug

    Zidovudine

    go.drugbank.com/drugs/DB00495
    ApprovedInvestigational

    The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. … A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group.

    Mixtures: ZOVILAM PED DT®, N/ACategories: Antivirals used in combination for the treatment of HIV infections
  9. Drug

    Cinnamaldehyde

    go.drugbank.com/drugs/DB14184
    Approved

    It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to cinnamaldehyde may be identified with a clinical patch test. … Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.