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PF-00446687
go.drugbank.com/drugs/DB12517InvestigationalPF-00446687 has been investigated for the treatment of Erectile Dysfunction.
PD-173952
go.drugbank.com/drugs/DB17041ExperimentalPD-173952 is a potent Myt1 kinase inhibitor.[A253067]
Mevidalen
go.drugbank.com/drugs/DB19034InvestigationalMevidalen is under investigation in clinical trial NCT03305809 (A Study of LY3154207 in Participants With Dementia Due to Lewy Body Dementia (LBD) Associated With Idiopathic Parkinson's Disease (PD) or
Roxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigationalRoxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transc...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesEthylenediamine
go.drugbank.com/drugs/DB14189ApprovedEthylenediamine is an organic compound that is used as a building block for the production of many other chemical products. … It is also used as an excipient in many pharmacological preparations such as creams. Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions [A34285].
PF-04217903
go.drugbank.com/drugs/DB12848InvestigationalPF-04217903 has been used in trials studying the treatment of Neoplasms.
PF-477736
go.drugbank.com/drugs/DB12611InvestigationalPF-00477736 has been used in trials studying the treatment of Neoplasms.
Carvedilol
go.drugbank.com/drugs/DB01136ApprovedInvestigationalCarvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Nu-carvedilol, Ran-carvedilolEdrophonium
go.drugbank.com/drugs/DB01010ApprovedIt has also been used as an antidote to curare principles.