PF-00446687

DB12517InvestigationalSmall molecule

PF-00446687 has been investigated for the treatment of Erectile Dysfunction.

Mechanism: Pharmacologically active on Melanocortin receptor 4
Curator reviewed
Formula / weight: C₂₈H₃₆F₂N₂O₂ · 470.605 g/mol (avg)
Code names: (-)-PF-00446687

Resolves to

Compound

Structure

InChIKeyWHPJOAUPIZDJNX-AGGGUQDCSA-NSMILESC[C@H]1CN(C[C@@H](C)[C@]1(O)C1=CC=CC=C1)C(=O)[C@@H]1CN(C[C@H]1C1=CC=C(F)C=C1F)C(C)(C)C

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with PF-00446687, and which of those have an active Phase 3 trial?

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