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Isosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigational[L11743] Isosorbide mononitrate has a longer duration of action than [nitroglycerin] due to its slow onset of absorption and metabolism. … Like other organic nitrates, isosorbide mononitrate acts as a prodrug for its active metabolite, [nitric oxide], which mediates the therapeutic action of isosorbide mononitrate.
Synonyms: IS 5-MN, IS-5-MNProducts: ISMN AL 100 RETARD, ISMN AL 20Antihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalAntihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated … with at least one molecule of polyethylene glycol (MW 20 kDa) [FDA label].
Categories: Compounds used in a research, industrial, or household settingProducts: ADYNOVATE 500®IU / VIAL, ADYNOVATE®250IU/VIALMethocarbamol
go.drugbank.com/drugs/DB00423ApprovedInvestigationalVet approvedMethocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. … [Label,L6268] In Canada, methocarbamol can be sold as an over the counter oral medicine at a lower dose that may be combined with [acetaminophen] or [ibuprofen].
Mixtures: SINAXAR ® A TABLETAS, METOCARBAMOL 500 MG + IBUPROFENO 200 MG TABLETAS RECUBIERTASSynonyms: (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamateNebivolol
go.drugbank.com/drugs/DB04861ApprovedInvestigationalNebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. … [A182594] Nebivolol was granted FDA approval on 17 December 2007.[L7985]
Mixtures: AMLONEB 10 MG/5 MG TABLET, 30 ADET, AMLONEB 10 MG/5 MG TABLET, 90 ADETCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AgonistsFluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalFluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. … As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: VERLIN TABLETAS X 50 MG, FAVERIN 100 MGEbastine
go.drugbank.com/drugs/DB11742ApprovedInvestigationalWithdrawnEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: PINAVALT® 10 MG TABLETASRECUBIERTAS, EBAFIT 20 MG FILM KAPLI TABLET, 10 ADETArsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalIn general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects. … The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: LEUSENOX 10 MG/10 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 1 ADET, TRISENOX 1 MG/1 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 ADETCalfactant
go.drugbank.com/drugs/DB06415ApprovedInvestigationalCalfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. … Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg of proteins including surfactant-associated
Synonyms: SF-RI 1Products: INFASURF 35 MG/ML INTRATRAKEAL SÜSPANSIYON ,6 ML, INFASURF 35 MG/ML INTRATRAKEAL SÜSPANSIYON,3 MLApixaban
go.drugbank.com/drugs/DB06605ApprovedInvestigationalApixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic … Apixaban was approved by the FDA on December 28, 2012[L6043].
Categories: Factor Xa Inhibitors, Direct factor Xa inhibitorsProducts: Apixaban 1A Pharma 5 mg – Filmtabletten, Apixaban 1A Pharma 2,5 mg – FilmtablettenFerric carboxymaltose
go.drugbank.com/drugs/DB08917ApprovedInvestigationalFerric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Categories: Compounds used in a research, industrial, or household settingProducts: Ferapplic 500 mg/10 ml Enjeksiyonluk/İnfüzyonluk Çözelti, 1 flakon, Ferapplic 500 mg/10 ml Enjeksiyonluk/İnfüzyonluk Çözelti, 5 flakon