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Displaying results 151 - 160 of 144565 in total
  1. Drug

    Fluorescein

    go.drugbank.com/drugs/DB00693
    ApprovedInvestigational

    injuries and corneal trauma. … A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal

    Mixtures: Minims Lidocaine and Fluorescein, Fluorescein Sodium and Proparacaine HydrochlorideCategories: Indicators and Reagents
  2. Drug

    Nogapendekin alfa

    go.drugbank.com/drugs/DB18740
    ApprovedInvestigational

    [A263617, A263622] Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which … Nogapendekin alfa is a human IL-15N72D variant.

    Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsSynonyms: Fusion protein consisting of il-15n72d and il-15rasu/fc, IL-15N72D
  3. Drug

    Goflikicept

    go.drugbank.com/drugs/DB16396
    Investigational

    Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe

    Categories: Antineoplastic and Immunomodulating AgentsSynonyms: Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein
  4. Drug

    CHF5633

    go.drugbank.com/drugs/DB18696
    Investigational

    CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue
  5. Drug

    DCVAC/OvCa

    go.drugbank.com/drugs/DB18571
    Investigational

    DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand _ex vivo_.

    Synonyms: Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo
  6. Drug

    Streptococcus salivarius

    go.drugbank.com/drugs/DB19274
    Investigational

    Synonyms: Streptococcus salivarius andrewes and horder, 1906
  7. Drug

    VOR33

    go.drugbank.com/drugs/DB18624
    Investigational

    VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.

    Synonyms: allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein
  8. Drug

    TPX-4589

    go.drugbank.com/drugs/DB18604
    Investigational

    TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.

    Synonyms: Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE
  9. Drug

    ARGX-119

    go.drugbank.com/drugs/DB18133
    Investigational

    ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).

    Synonyms: a fully humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and activates MuSK
  10. Drug

    GTP-506

    go.drugbank.com/drugs/DB17682
    Experimental

    GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide

    Synonyms: Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and AAVrh79.hHDR.TBG.hOTCco.bGH