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Displaying results 151 - 160 of 8602 in total
  1. Drug

    Lecanemab

    go.drugbank.com/drugs/DB14580
    ApprovedInvestigational

    [A253962,L44547] On January 6, 2023, lecanemab was granted accelerated approval by the FDA for the treatment of Alzheimer’s Disease.[L44547] It was granted full FDA approval on July 6, 2023.

    Products: LEQEMBI 100mg/mL concentrate for solution for infusion (2mL), LEQEMBI 100mg/mL concentrate for solution for infusion (5mL)
  2. Drug

    Clindamycin

    go.drugbank.com/drugs/DB01190
    ApprovedInvestigationalVet approved

    [L11593] It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. … Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris.

    Mixtures: CLINDAMICINA / CLOTRIMAZOL 100MG/200MG, CLINDAMICINA/KETOCONAZOL 100 MG/400MGProducts: INFEX 100MG CÁPSULA DE GELATINA BLANDA, SOBELIN 150MG
  3. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488] … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.

    Mixtures: N-ACETILCISTEÍNA MAS GUAYACOLATO DE GLICERILO, ASCOVIT 900/300MG SAŞE, 20 SAŞEProducts: BROMUC AKUT JUNIOR 100MG, N - ACETILCISTEINA 100MG
  4. Drug

    Didanosine

    go.drugbank.com/drugs/DB00900
    ApprovedInvestigational

    A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative

    Products: Videx Chewable Dispersible Tab 100mg, Videx Chewable Dispersible Tab 150mg
  5. Drug

    Larotrectinib

    go.drugbank.com/drugs/DB14723
    ApprovedInvestigational

    [L49821] Larotrectinib was granted accelerated approval by the FDA in November 2018 for the treatment of Trk-positive solid tumors. … It was notable for being the second tissue-agnostic chemotherapy ever approved by the FDA.[L4847]. On April 10, 2025, the FDA granted full drug approval.[L52805]

    Products: VITRAKVI®CÁPSULAS DE 100MG, VITRAKVI HARD CAPSULE 100MG
  6. Drug

    Allopurinol

    go.drugbank.com/drugs/DB00437
    ApprovedInvestigational

    It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677]. … This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals [A175942].

    Products: Purinol Tab 100mg, CLINT TABLET 100MG
  7. Drug

    Fluvoxamine

    go.drugbank.com/drugs/DB00176
    ApprovedInvestigational

    Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients. … It was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine.

    Products: FEVARIN 100MG, Gen-fluvoxamine 100mg
  8. Drug

    Entrectinib

    go.drugbank.com/drugs/DB11986
    ApprovedInvestigational

    [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval based on early trial data. … This therapy offers benefit over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib] due to a wider range of targets.[A183929]

    Products: ROZLYTREK HARD CAPSULE 100MG, ROZLYTREK CÁPSULAS DURAS 100MG
  9. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    [A175249] It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults. … [A175249] Interestingly, topiramate was discovered by chance when attempts were made to formulate a novel antidiabetic drug.[A188330]

    Synonyms: 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamateProducts: Topamax 100mg, TOPAMAX 100MG
  10. Drug

    Clozapine

    go.drugbank.com/drugs/DB00363
    ApprovedInvestigational

    Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. … [A256718] Clozapine was approved by the FDA in 1989 for treatment-resistant schizophrenia under the brand CLOZARIL.

    Products: LEPONEX 100MG, CLOZAPIN BETA 100MG