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Displaying results 1591 - 1600 of 10000 in total
  1. Drug

    Buprenorphine

    go.drugbank.com/drugs/DB00921
    ApprovedIllicitInvestigationalVet approved

    [A186263,A186266,A186269] Buprenorphine acts as a partial mu-opioid receptor agonist with a high affinity for the receptor, but lower intrinsic activity compared to other full mu-opioid agonists such … Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.

    Synonyms: 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2-butanol, 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanolMixtures: Bupensan Duo 8 mg/2 mg-Sublingualtabletten, Bupensan Duo 2 mg/0,5 mg-Sublingualtabletten
  2. Drug

    N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide

    go.drugbank.com/drugs/DB08235
    Experimental

    Synonyms: N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide
  3. Drug

    MAK-683

    go.drugbank.com/drugs/DB19205
    Investigational

    Synonyms: 1,2,4-TRIAZOLO(4,3-C)PYRIMIDIN-5-AMINE, N-((5-FLUORO-2,3-DIHYDRO-4-BENZOFURANYL)METHYL)-8-(2-METHYL-3-PYRIDINYL)-, N-((5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl)-8-(2-methylpyridin-3-yl)(1,2,4)triazolo(4,3-c)pyrimidin-5-amine
  4. Drug

    2,2'-Dibenzothiazyl disulfide

    go.drugbank.com/drugs/DB14201
    Approved

    It is also a known allergen and dermatological sensitizer. Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.

    Synonyms: di(1,3-benzothiazol-2-yl) disulfide, 2-Benzothiazolyl disulfideCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-Ring
  5. Drug

    Nanvuranlat

    go.drugbank.com/drugs/DB18250
    Investigational

    Synonyms: L-tyrosine, o-((5-amino-2-phenyl-7-benzoxazolyl)methyl)-3,5-dichloro-, O-((5-amino-2-phenyl-1,3-benzoxazol-7-yl)methyl)-3,5- dichloro-l-tyrosineCategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    (E)-(4S,6S)-6-((S)-2-{(S)-2-[(FURAN-2-CARBONYL)-AMINO]-3-METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)-8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID ETHYL ESTER

    go.drugbank.com/drugs/DB04613
    Experimental

    Synonyms: (E)-(4S,6S)-6-((S)-2-{(S)-2-[(FURAN-2-CARBONYL)-AMINO]-3-METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)-8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID ETHYL ESTER
  7. Drug

    Tibolone

    go.drugbank.com/drugs/DB09070
    ApprovedInvestigational

    It has been used in Europe for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and the treatment of post-menopausal symptoms [L1720]. … Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha [L1874].

    Synonyms: 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-oneProducts: TIBONELLA® TABLETAS 2.5 MG, TINOX® 2.5 MG COMPRIMIDOS
  8. Drug

    Enitociclib

    go.drugbank.com/drugs/DB17297
    Investigational

    Synonyms: 2-pyridinamine, 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-(4-(((s(s))-s-methylsulfonimidoyl)methyl)-2-pyridinyl)-
  9. Drug

    Conivaptan

    go.drugbank.com/drugs/DB00872
    Approved

    Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). … Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).

    Synonyms: 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilideCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  10. Drug

    PF-5212372

    go.drugbank.com/drugs/DB19212
    Investigational

    PF-5212372 is under investigation in clinical trial NCT02795832 (A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and in Subjects With Atopic Dermatitis).

    Synonyms: Benzenepropanoic acid, 4-((2-(5-chloro-1-(diphenylmethyl)-2-(2-((((2-(trifluoromethyl)phenyl)methyl)sulfonyl)amino)ethyl)-1h-indol-3-yl)ethyl)sulfonyl)-Categories: Phospholipase A2 Inhibitors