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Displaying results 1591 - 1600 of 10000 in total
  1. Drug

    Tanfanercept

    go.drugbank.com/drugs/DB19142
    Investigational

    Tanfanercept is under investigation in clinical trial NCT06400589 (A Study to Evaluate the Efficacy and Safety of Tanfanercept (HL036) in Dry Eye Disease).

    Synonyms: L-methionyl-(l28>v,s52>m,h55>f,r57>p,h58>g,k121>n) tumor necrosis factor (tnf) binding protein variant 1 (tbp-1) with c-terminal extension by further 10 residues of the pro-protein, human, unglycosylated, 41-211-tumor necrosis factor receptor 1
  2. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    Azithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine].

    Categories: Experimental Unapproved Treatments for COVID-19, P-glycoprotein inhibitorsProducts: AZITHROMYCIN FOR INJECTION 500 MG/VIAL , 10 ML LYO VIAL, AZITIN 200 MG/5 ML ORAL SÜSPANSIYON IÇIN KURU TOZ, 15 ML
  3. Drug

    Linafexor

    go.drugbank.com/drugs/DB18031
    Investigational

    Synonyms: 1,2,4-OXADIAZOL-5(2H)-ONE, 3-(4-(3-((5-CYCLOPROPYL-3-(2,6-DICHLOROPHENYL)-4-ISOXAZOLYL)METHOXY)-8-AZABICYCLO(3.2.1)OCT-8-YL)-2-FLUOROPHENYL)-, 3-(4-((3-endo)-3-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4- yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-2-fluorophenyl)-1,2,4-oxadiazol-5(4H)-oneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    Phenazepam

    go.drugbank.com/drugs/DB19164
    Investigational

    Phenazepam is under investigation in clinical trial NCT03017430 (Pregabalin for Opiate Withdrawal Syndrome).

    Synonyms: 2h-1,4-benzodiazepin-2-one, 1,3-dihydro-7-bromo-5-(2-chlorophenyl)-, 2h-1,4-benzodiazepin-2-one, 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Gemcitabine elaidate

    go.drugbank.com/drugs/DB12564
    Investigational

    Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.

    Synonyms: 5'-O-(TRANS-9''-OCTADECENOYL)-1-.BETA.-D-2'DEOXY-2',2'-DIFLUOROCYTIDINE, 5'-O-(trans-9"-octadecenoyl)-1-beta-D-2'deoxy-2',2'-difluorocytidineCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Imolamine

    go.drugbank.com/drugs/DB09284
    Investigational

    Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl-4,5-dihydro-1,2,3-oxadiazol,-4-yl)ethyl]amine. … It is developed under the brand name Coremax by Novartis consumer health SA.

    Synonyms: 3-Phenyl-4-diethylaminoethyl-5-imino-1,2,4-oxadiazolCategories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Tuvusertib

    go.drugbank.com/drugs/DB18790
    Investigational

    Synonyms: 2-amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
  8. Drug

    alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14003
    Approved

    The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months … = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years [L2120].

    Synonyms: Vitamin E acetate, Vitamin E (alpha tocopherol acetate)Mixtures: PNV Tabs 20-1, Vitamin E 400 I.U. & Selenium 50 Mcg Capsules
  9. Drug

    Cisplatin

    go.drugbank.com/drugs/DB00515
    ApprovedInvestigational

    It was the first member of its class, which now also includes carboplatin and oxaliplatin. … Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung

    Synonyms: (SP-4-2)-DIAMMINEDICHLOROPLATINUM, PLATINUM, DIAMMINEDICHLORO-, (SP-4-2)-Categories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  10. Drug

    Sunvozertinib

    go.drugbank.com/drugs/DB18925
    Investigational

    receptor (EGFR) exon 20 insertion mutations. … [A274143] Sunvozertinib was granted accelerated approval in the US on July 2, 2025 for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor

    Synonyms: 2-Propenamide, N-[5-[[4-[[5-chloro-4-fluoro-2-(1-hydroxy-1- methylethyl)phenyl]amino]-2-pyrimidinyl]amino]-2-[(3R)-3-(dimethylamino)-1-pyrrolidinyl]-4-methoxyphenyl]-, N-{5-[(4-{[5-chloro-4-fluoro-2-(1-hydroxy-1-methylethyl)phenyl]amino}pyrimidin-2-yl)amino]-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl}prop-2-enamideCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitors