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Displaying results 1621 - 1630 of 10000 in total
  1. Drug

    Scriptaid

    go.drugbank.com/drugs/DB17053
    Experimental

    Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.[A253127]

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 1h-benz(de)isoquinoline-2(3h)-hexanamide, n-hydroxy-1,3-dioxo-, N-hydroxy-1,3-dioxo-1h-benz(de)isoquinoline-2(3h)-hexan amide
  2. Drug

    SKF-96365 free base

    go.drugbank.com/drugs/DB17054
    Experimental

    SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists.[A253132]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole
  3. Drug

    SNX-2112

    go.drugbank.com/drugs/DB17055
    Experimental

    SNX-2112 is a heat shock protein 90 (Hsp90) inhibitor.[A253137]

    Synonyms: Benzamide, 2-((trans-4-hydroxycyclohexyl)amino)-4-(4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1h-indazol-1-yl)-
  4. Drug

    JZP-386 free base

    go.drugbank.com/drugs/DB17068
    Experimental

    JZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.

  5. Drug

    LY3884961

    go.drugbank.com/drugs/DB17070
    Investigational

    LY3884961 (previously PR001) is being developed by Prevail Therapeutics as a single-dose gene therapy for patients with Parkinson's disease and Gaucher disease.[L43468]

  6. Drug

    MYR-101

    go.drugbank.com/drugs/DB17075
    Investigational

    It is caused by a mutation in the aspartoacylase gene (_ASPA_), which leads to a deficiency of the aspartoacylase enzyme (ASPA). … ASPA is produced in oligodendrocytes, and participates in the metabolism of N-acetylaspartate (NAA).

  7. Drug

    Sipagladenant

    go.drugbank.com/drugs/DB17080
    Investigational

    KW-6356 is a selective antagonist of adenosine A2A receptors developed by Kyowa Kirin.[L43822]

  8. Drug

    Tinlorafenib

    go.drugbank.com/drugs/DB17082
    Investigational

    Tinlorafenib (PF-07284890) is a potent, selective, highly brain-penetrant, small-molecule inhibitor of BRAF V600 mutations.[A253992]

    Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Gadopiclenol

    go.drugbank.com/drugs/DB17084
    ApprovedInvestigational

    Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. … [A254002] Gadopiclenol has high kinetic stability and a high r1 relaxivity, allowing it to be used at lower doses than classic extracellular GBCAs.

    Synonyms: 2-[3,9-bis[1-carboxylato-4-(2,3-dihydroxypropylamino)-4-oxobutyl]-3,6,9,15-tetrazabicyclo[9.3.1]pentadeca-1(15),11,13-trien-6-yl]-5-(2,3-dihydroxypropylamino)-5-oxopentanoate;gadolinium(3+), (.alpha.3,.alpha.6,.alpha.9-tris(3-((2,3-dihydroxypropyl)amino)-3-oxopropyl)-3,6,9,15-tetraazabicyclo(9.3.1)pentadeca-1(15),11,13-triene-3,6,9-triacetato(3-)-.kappa.n3,.kappa.n6,.kappa.n9,.kappa.n15,.kappa.o3
  10. Drug

    KDT-3594

    go.drugbank.com/drugs/DB17085
    Investigational

    KDT-3594 is a non-ergot dopamine receptor agonist developed by Kissei Pharmaceutical.