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Milsaperidone
go.drugbank.com/drugs/DB24348ApprovedInvestigationalMilsaperidone is an atypical antipsychotic agent that rapidly interconverts to [iloperidone] in vivo. … [L56056] On February 20, 2026, milsaperidone was approved by the FDA for the treatment of Bipolar I Disorder and schizophrenia.[L56059]
Meningococcal polysaccharide vaccine group C
go.drugbank.com/drugs/DB13890ApprovedInvestigational*N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. … It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup C.
Mixtures: Menjugate 10 Mikrogramm Injektionssuspension in einer Fertigspritze, Menomune-A/c/y/w-135Peginterferon alfa-2a
go.drugbank.com/drugs/DB00008ApprovedInvestigationalIn a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) no longer recommend Peginterferon alfa … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852].
Synonyms: PEG-IFN alfa-2A, PEG-Interferon alfa-2ACategories: Interferon Type I, Compounds used in a research, industrial, or household settingFondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalFondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. … angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI); and in the management of ST segment elevation myocardial infarction (STEMI).
Categories: Factor Xa Inhibitors, Indirect factor Xa inhibitorsDordaviprone
go.drugbank.com/drugs/DB14844ApprovedInvestigationalDordaviprone is a first-in-class small molecule imipridone. On August 6, 2025, dordaviprone was granted accelerated approval by the FDA. … [L53838] It is used to treat patients with diffuse midline glioma harboring an H3 K27M mutation.
Synonyms: 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo(1,2-A)pyrido(3,4-E)pyrimidin-5(4H)-one, 2,4,6,7,8,9-Hexahydro-4-((2-methylphenyl)methyl)-7-phenylmethyl)imidazo)(1,2-a)pyrido(3,4-e)pyrimidin-5(1H)-oneTiopronin
go.drugbank.com/drugs/DB06823ApprovedTiopronin is used as a second-line therapy to control the rate of cystine precipitation and excretion, and prevent kidney stone formation. … It is similar to d-penicillamine in use and efficacy, but offers the advantage of far less adverse effects.
International brands: Kai NaCategories: N-substituted GlycinesThrombin alfa
go.drugbank.com/drugs/DB11572ApprovedThrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. … The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious agents.
Cipaglucosidase alfa
go.drugbank.com/drugs/DB16708ApprovedInvestigationalby a deficiency in GAA. … Cipaglucosidase alfa is conjugated with mannose-6-phosphate (M6P) N-glycans that bind to the cation-independent mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues
Nevirapine
go.drugbank.com/drugs/DB00238ApprovedInvestigationalA potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS.
Mixtures: Zidovex LN (Lamivudine 150mg, Zidovudine 300mg, Nevirapine 200mg Tablets), ZIMODINE N ®Categories: Antivirals used in combination for the treatment of HIV infectionsThyroid, porcine
go.drugbank.com/drugs/DB09100ApprovedInvestigational[A190831] Thyroid extract is no longer considered a first line therapy as it delivers a dose that is inconsistent with the stated strength of the tablet. … [A190813] Thyroid extracts were never FDA approved as their use in the United States predates the FDA.[A190831]