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VA-MENGOC-BC®
go.drugbank.com/drugs/DB15800ExperimentalThis vaccine may also induce moderate protection against N. gonorrhoeae. As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.
Melphalan flufenamide
go.drugbank.com/drugs/DB16627ApprovedWithdrawnMelphalan flufenamide, also known as melflufen or J1, is a prodrug of melphalan. Melphalan flufenamide is more readily uptaken by cells than melphalan, and is cleaved to the active metabolite by aminopeptidases. In vitro models show that...
N-oleoyldopamine
go.drugbank.com/drugs/DB17036ExperimentalN-oleoyldopamine (OLDA) is an amide of dopamine and oleic acid.[A253042]
Synonyms: N-oleoyldopamine, (9z)- n-(2-(3,4-dihydroxyphenyl)ethyl)-9-octadecenamideMYR-101
go.drugbank.com/drugs/DB17075InvestigationalASPA is produced in oligodendrocytes, and participates in the metabolism of N-acetylaspartate (NAA).
BHV-5000
go.drugbank.com/drugs/DB17817ExperimentalBHV-5000 is an orally bioavailable, low-trapping, potent N-methyl-D-aspartate (NMDA) receptor antagonist. The active metabolite of BHV-5000 is [lanicemine].[L46446]
Synonyms: (S)-1-(L-valyl)-N_((S)-1-phenyl-2-(pyridin-2-yl)ethyl)pyrrolidine-2-carboxamide fumarateKUR-113
go.drugbank.com/drugs/DB18413InvestigationalKUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone fragment. It is being investigated as a bioactive bone graft substitute.
Synonyms: Fibrin-based agent containing a N-terminally modified parathyroid hormone fragment TGplPTH1-34Sapablursen
go.drugbank.com/drugs/DB18608InvestigationalSapablursen is a synthetic 2'-O-(2-methoxyethyl)-modified antisense oligonucleotide linked to a tri-antennary cluster of N-acetyl galactosamine (GalNAc3) sugars targeting transmembrane protease, serine
Donidalorsen
go.drugbank.com/drugs/DB18751ApprovedInvestigationalHereditary angioedema (HAE) is a rare genetic disease characterized by recurrent episodes of severe swelling induced by excessive production of bradykinin. Donidalorsen is a ligand-conjugated antisense oligonucleotide that reduces plasma...
Arofylline
go.drugbank.com/drugs/DB20307ExperimentalThe usage of the INN stem '-fylline' in the name indicates that Arofylline is a N-methylated xanthine derivative. Arofylline has a monoisotopic molecular weight of 304.07 Da.