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Displaying results 161 - 170 of 151541 in total
  1. Drug

    Acetrizoic acid

    go.drugbank.com/drugs/DB09347
    ApprovedWithdrawn

    [L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status.[L1703] … Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid[L1702] and it is the first monomeric ionic compound used as an X-ray contrast agent.

    Synonyms: Urokonic acid, Acetrizoic acidCategories: acetrizoic acid, Acids, Carbocyclic
  2. Drug

    Levomefolic acid

    go.drugbank.com/drugs/DB11256
    Approved

    Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma … it methylates homocysteine and forms methionine and tetrahydrofolate (THF).

    Mixtures: Quflora FE, Vitafol Fe PlusCategories: Folic Acid and Derivatives, Amino Acids, Peptides, and Proteins
  3. Drug

    Tienilic acid

    go.drugbank.com/drugs/DB04831
    ApprovedWithdrawn

    It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982) … Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension.

    Categories: tienilic acid, Aryloxyacetic Acid DerivativesSynonyms: Tienilic acid, Thienylic acid
  4. Drug

    Gadoxetic acid

    go.drugbank.com/drugs/DB08884
    ApprovedInvestigational

    [A263146] Gadoxetic acid, under the form gadoxetate disodium, is marketed by Bayer HealthCare Pharmaceuticals under the brand name EOVIST and FDA approved in 2008.[A263151] … Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug.

    Categories: gadoxetic acid, Acids, AcyclicSynonyms: Gadoxetic acid, Gd-EOB-DTPA
  5. Drug

    Pidolic acid

    go.drugbank.com/drugs/DB03088
    ApprovedInvestigational

    Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form, like skin [L2729]. … Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics

    Mixtures: 2% Salicylic Acid FACIAL CLEANSERCategories: Amino Acids, Peptides, and Proteins, Alimentary Tract and Metabolism
  6. Drug

    Pamidronic acid

    go.drugbank.com/drugs/DB00282
    ApprovedInvestigational

    Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and [alendronic acid].[A203111] Pamidronic acid was first described in the literature in 1977. … [A203267] The second generation bisphosphonates are less common as third generation bisphosphonates, such as [ibandronic acid], [zoledronic acid], [minodronic acid], and [risedronic acid] are becoming

    Synonyms: Pamidronic acid, Acide pamidroniqueCategories: Drugs Affecting Bone Structure and Mineralization, pamidronic acid
  7. Drug

    Obeticholic acid

    go.drugbank.com/drugs/DB05990
    ApprovedInvestigational

    [A18696,L12633] In May 2021, the FDA updated its prescribing information to contraindicate the use of obeticholic acid in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected to be granted full approval for this indication in 2020.[L12636]

    Categories: Bile Acids and Salts, Bile acids and derivativesSynonyms: Obeticholic acid, 6-ethylchenodeoxycholic acid
  8. Drug

    Iopanoic acid

    go.drugbank.com/drugs/DB08946
    ApprovedWithdrawn

    Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.

    Categories: iopanoic acidSynonyms: Iopanoic acid, Iodopanoic acid
  9. Drug

    Tauroursodeoxycholic acid

    go.drugbank.com/drugs/DB08834
    ApprovedInvestigationalWithdrawn

    [A249060] Normally, hydrophilic bile acids regulates hydrophobic bile acids and their cytotoxic effects. … [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as a bile acid derivative.

    Synonyms: Tauroursodeoxycholic acid, Tauroursodesoxycholic acidSalts: Tauroursodeoxycholic acid dihydrate
  10. Drug

    Ioxitalamic acid

    go.drugbank.com/drugs/DB13444
    ApprovedWithdrawn

    [A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. … Ioxitalamate is an ionic iodinated contrast medium.[A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg.

    Synonyms: Ioxitalamic acid, Acide ioxitalamiqueCategories: ioxitalamic acid, Acids, Carbocyclic