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Displaying results 161 - 170 of 14509 in total
  1. Drug

    Esketamine

    go.drugbank.com/drugs/DB11823
    ApprovedInvestigational

    and therapies. … Major depressive disorder (MDD) is a significant cause of disability worldwide and the most common illness preceding suicide.

    Categories: Non-Competitive N-Methyl D-Aspartate (NMDA) Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone, L-ketamine
  2. Drug

    Etoposide

    go.drugbank.com/drugs/DB00773
    ApprovedInvestigational

    Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. … A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.

    Categories: Antineoplastic and Immunomodulating Agents, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside), 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one
  3. Drug

    PlasmaCord

    go.drugbank.com/drugs/DB16363
    Experimental

    PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental blood. … [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).

    Synonyms: Human umbilical cord and placental blood plasma
  4. Drug

    4,6-O-(1-Carboxyethylidene)-Beta-D-Glucose

    go.drugbank.com/drugs/DB04386
    Experimental

    Synonyms: 4,6-O-(1-Carboxyethylidene)-Beta-D-Glucose
  5. Drug

    Cloxacillin

    go.drugbank.com/drugs/DB01147
    ApprovedInvestigationalVet approved

    A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin].

    Categories: combinations of penicillins, Heterocyclic Compounds, 2-RingSynonyms: (3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin, 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid
  6. Drug

    VA-MENGOC-BC®

    go.drugbank.com/drugs/DB15800
    Experimental

    VA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. … The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide of meningococcal group C.

    Synonyms: Meningococcal polysaccharide vaccine groups B and C
  7. Drug

    2-Aminobenzyl alcohol

    go.drugbank.com/drugs/DB03058
    Experimental

    Synonyms: o-Aminobenzyl alcohol, o-(Hydroxymethyl)aniline
  8. Drug

    Tirofiban

    go.drugbank.com/drugs/DB00775
    ApprovedInvestigational

    It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation. … Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery.

    Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsSynonyms: N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine, (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid
  9. Drug

    3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME

    go.drugbank.com/drugs/DB08334
    Experimental

    Synonyms: 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME
  10. Drug

    [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE]

    go.drugbank.com/drugs/DB04597
    Experimental

    Synonyms: [4,6-O-(1-CARBOXYETHYLIDENE)-BETA-D-MANNOSE]