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Displaying results 161 - 170 of 144663 in total
  1. Drug

    Afamelanotide

    go.drugbank.com/drugs/DB04931
    Approved

    [L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125] … [L9086] It differs structurally from its endogenous counterpart by only two amino acids - these structural differences improve biological efficacy by imparting a greater affinity for its target and a longer

    Salts: Afamelanotide acetateCategories: Indicators and Reagents, Amino Acids, Peptides, and Proteins
  2. Drug

    Bazedoxifene

    go.drugbank.com/drugs/DB06401
    ApprovedInvestigational

    It is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy. … In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the FDA for the treatment of moderate to severe vasomotor symptoms associated with menopause, as well as

    Salts: Bazedoxifene acetateCategories: Genito Urinary System and Sex Hormones, conjugated estrogens and bazedoxifene
  3. Drug

    Tetracosactide

    go.drugbank.com/drugs/DB01284
    ApprovedInvestigational

    Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all...

    Salts: Tetracosactide acetateCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and Insulins
  4. Drug

    Macimorelin

    go.drugbank.com/drugs/DB13074
    Approved

    and diagnosis of AGHD. … They include treatment for growth retardation in children and cachexia associated with chronic disease such as AIDS and cancer.

    Salts: Macimorelin acetateCategories: Amino Acids, Peptides, and Proteins
  5. Drug

    Rusfertide

    go.drugbank.com/drugs/DB17724
    ApprovedInvestigational

    [L64098] Rusfertide is administered by subcutaneous injection and titrated to maintain hematocrit below 45%. … [L64098] It is a synthetic cyclic peptide that blocks the iron transporter ferroportin, reducing the availability of iron for red blood cell production and lowering hematocrit.

    Salts: Rusfertide acetateCategories: Blood and Blood Forming Organs, Amino Acids, Peptides, and Proteins
  6. Drug

    Tarlatamab

    go.drugbank.com/drugs/DB17256
    ApprovedInvestigational

    [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed … across various SCLC disease stages and treatment statuses.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific
  7. Drug

    SP1049C

    go.drugbank.com/drugs/DB04978
    Experimental

    Median survival is encouraging and correlates strongly with dose levels.[A260416] … SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic block copolymers.

    Synonyms: doxorubicin with pluronics F-127 and L-61, Doxorubicin HCl with pluronic L-61 and pluronic F-127
  8. Drug

    Ethynodiol diacetate

    go.drugbank.com/drugs/DB00823
    Approved

    A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. … Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug

    Synonyms: Etynodiol acetate, 17α-Ethynylestr-4-ene-3β,17β-diol acetateMixtures: Ethynodiol Diacetate and Ethinyl Estradiol, Ethynodiol Diacetate and Ethinyl Estradiol
  9. Drug

    (2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE

    go.drugbank.com/drugs/DB07955
    Experimental

    Synonyms: (2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE
  10. Drug

    Calendula officinalis flower

    go.drugbank.com/drugs/DB14263
    Approved

    It is not an approved drug.

    Synonyms: Calendula Officinalis Flower Water